High-Content Aloe vera Based Hydrogels: Physicochemical and Pharmaceutical Properties

M Chelu, M Popa, EA Ozon, J Pandele Cusu… - Polymers, 2023 - mdpi.com
The present research focuses on the physicochemical and pharmacotechnical properties of
new hydrogels obtained using allantoin, xanthan gum, salicylic acid and different …

Antibacterial and antibiofilm effects of different samples of five commercially available essential oils

R Neagu, V Popovici, LE Ionescu, V Ordeanu… - Antibiotics, 2023 - mdpi.com
Essential oils (EOs) have gained economic importance due to their biological activities, and
increasing amounts are demanded everywhere. However, substantial differences between …

Design, Characterization, and Anticancer and Antimicrobial Activities of Mucoadhesive Oral Patches Loaded with Usnea barbata (L.) FH Wigg Ethanol Extract F-UBE …

V Popovici, E Matei, GC Cozaru, L Bucur, CE Gîrd… - Antioxidants, 2022 - mdpi.com
The oral cavity's common pathologies are tooth decay, periodontal disease, and oral cancer;
oral squamous cell carcinoma (OSCC) is the most frequent oral malignancy, with a high …

Cytotoxicity Analysis and In Silico Studies of Three Plant Extracts with Potential Application in Treatment of Endothelial Dysfunction

AR Ungureanu, V Popovici, C Oprean, C Danciu… - Pharmaceutics, 2023 - mdpi.com
Endothelial dysfunction is the basis of the physiopathological mechanisms of vascular
diseases. In addition to the therapeutic activity of plant extracts, cytotoxicity is significant …

[HTML][HTML] Self-assembled chitosan-sodium usnate drug delivery nanosystems: Synthesis, characterization, stability studies, in vitro cytotoxicity and in vivo …

B Brugnoli, A Mariano, B Simonis, C Bombelli… - Carbohydrate Polymer …, 2023 - Elsevier
Polymers are among the most studied materials as drug carriers, due to their tunable
chemical structure and ability to self-assemble to give different types of nanostructures. In …

[HTML][HTML] Molecular Targets of Plant-Derived Bioactive Compounds in Oral Squamous Cell Carcinoma

G Mitea, V Schröder, IM Iancu, H Mireșan, V Iancu… - Cancers, 2024 - mdpi.com
Background: With a significant increase in both incidence and mortality, oral cancer—
particularly oral squamous cell carcinoma (OSCC)—is one of the main causes of death in …

ROS-Induced DNA-Damage and Autophagy in Oral Squamous Cell Carcinoma by Usnea barbata Oil Extract—An In Vitro Study

V Popovici, AM Musuc, E Matei, O Karampelas… - International Journal of …, 2022 - mdpi.com
Oxidative stress is associated with aging, cancers, and numerous metabolic and chronic
disorders, and phenolic compounds are well known for their health-promoting role due to …

Three-Dimensional Printing Technologies in Oral Films Manufacturing—A Minireview

EA Ozon, I Sarbu, V Popovici, MA Mitu, AM Musuc… - Processes, 2023 - mdpi.com
The interest in buccal drug delivery is under consideration due to some distinct properties
compared to the traditional pharmaceutical formulations for oral administration: significantly …

[HTML][HTML] Porphyrin Photosensitizers into Polysaccharide-Based Biopolymer Hydrogels for Topical Photodynamic Therapy: Physicochemical and Pharmacotechnical …

AM Burloiu, EA Ozon, AM Musuc, M Anastasescu… - Gels, 2024 - mdpi.com
Photodynamic therapy (PDT) is an emerging treatment modality that utilizes light-sensitive
compounds, known as photosensitizers, to produce reactive oxygen species (ROS) that can …

Dermatocosmetic Emulsions Based on Resveratrol, Ferulic Acid and Saffron (Crocus sativus) Extract to Combat Skin Oxidative Stress-Trigger Factor of Some …

D Turcov, AS Barna, AC Blaga, C Ibanescu, M Danu… - Pharmaceutics, 2022 - mdpi.com
The increasing incidence of skin diseases, against the background of increased pollution,
urbanism, poor habits in lifestyle, work, rest, diet and general medication, led to the …