Epigenetics is the epi-information beyond the DNA sequence that can be inherited from
parents to offspring. From years of studies, people have found that histone modifications …

Abstract Recently, super-enhancers (SEs) have been identified as a unique type of
transcriptional regulation involved in cancer development. SEs exhibit a size, high …

Enhancers are distal cis-regulatory elements that activate the transcription of their target
genes. They regulate a wide range of important biological functions and processes …

Cancer cells survive cellular crisis through telomere maintenance mechanisms. We report
telomere lengths in 18,430 samples, including tumors and non-neoplastic samples, across …

Super-enhancers (SEs) are cell-specific DNA cis-regulatory elements that can supervise the
transcriptional regulation processes of downstream genes. SEdb 2.0 (http://www. licpathway …

Chromatin features are widely used for genome-scale map** of enhancers. However,
discriminating active enhancers from other cis-regulatory elements, predicting enhancer …

Abstract The University of California Santa Cruz Genome Browser website (https://genome.
ucsc. edu) enters its 20th year of providing high-quality genomics data visualization and …

The early steps of HIV-1 infection, such as uncoating, reverse transcription, nuclear import,
and transport to integration sites are incompletely understood. Here, we imaged nuclear …

To increase understanding of the genomic landscape of acral melanoma, a rare form of
melanoma occurring on palms, soles or nail beds, whole genome sequencing of 87 tumors …

We studied how intratumoral genetic heterogeneity shapes tumor growth and therapy
response for isocitrate dehydrogenase (IDH)-wild-type glioblastoma, a rapidly regrowing …