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Multifaceted influence of histone deacetylases on DNA damage repair: implications for hepatocellular carcinoma
G Du, R Yang, J Qiu, J **a - Journal of Clinical and …, 2022 - pmc.ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the most commonly diagnosed cancers and a
leading cause of cancer-related mortality worldwide, but its pathogenesis remains largely …
leading cause of cancer-related mortality worldwide, but its pathogenesis remains largely …
PARP1 as an Epigenetic Modulator: Implications for the Regulation of Host-Viral Dynamics
AA Sobotka, I Tempera - Pathogens, 2024 - mdpi.com
The principal understanding of the Poly (ADP-ribose) polymerase (PARP) regulation of
genomes has been focused on its role in DNA repair; however, in the past few years, an …
genomes has been focused on its role in DNA repair; however, in the past few years, an …
The miR-590-3p/CFHR3/STAT3 signaling pathway promotes cell proliferation and metastasis in hepatocellular carcinoma
Z Wan, X Li, X Luo, B Wang, X Zhou… - Aging (Albany NY …, 2022 - pmc.ncbi.nlm.nih.gov
Accumulating evidence has indicated that Complement factor H-related 3 (CFHR3) plays an
essential role in various diseases. However, the biological functions of CFHR3 in …
essential role in various diseases. However, the biological functions of CFHR3 in …
Beta human papillomavirus 8E6 promotes alternative end joining
Double strand breaks (DSBs) are one of the most lethal DNA lesions in cells. The E6 protein
of beta-human papillomavirus (HPV8 E6) impairs two critical DSB repair pathways …
of beta-human papillomavirus (HPV8 E6) impairs two critical DSB repair pathways …
Cold tumour phenotype explained through whole genome sequencing in clinical nasopharyngeal cancer: a preliminary study
Handoko, M Adham, L Rachmadi… - ImmunoTargets and …, 2024 - Taylor & Francis
Introduction Nasopharyngeal cancer (NPC) is a complex cancer due to its unique genomic
features and association with the Epstein–Barr virus (EBV). Despite therapeutic …
features and association with the Epstein–Barr virus (EBV). Despite therapeutic …
Revised International Staging System (R-ISS) stage-dependent analysis uncovers oncogenes and potential immunotherapeutic targets in multiple myeloma (MM)
L Zhong, P Hao, Q Zhang, T Jiang, H Li, J **ao, C Li… - Elife, 2022 - elifesciences.org
Multiple myeloma (MM) accounts for~ 10% of all haematologic malignancies. Little is known
about high intratumour heterogeneities in patients stratified by the Revised International …
about high intratumour heterogeneities in patients stratified by the Revised International …
Polymerase theta is a synthetic lethal target for killing Epstein-Barr virus lymphomas
GH Willman, H Xu, TM Zeigler, MT McIntosh… - Journal of …, 2024 - journals.asm.org
ABSTRACT Treatment options for Epstein-Barr virus (EBV)-cancers are limited,
underscoring the need for new therapeutic approaches. We have previously shown that EBV …
underscoring the need for new therapeutic approaches. We have previously shown that EBV …
[HTML][HTML] EBV infection alters DNA methylation in primary human colon cells: A path to inflammation and carcinogenesis?
R Santarelli, GR Pascucci, SL Presti… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Abstract Epstein-Barr Virus (EBV) is associated with several types of human cancers, and
changes in DNA methylation are reported to contribute to viral-driven carcinogenesis …
changes in DNA methylation are reported to contribute to viral-driven carcinogenesis …
Multifaceted roles for STAT3 in gammaherpesvirus latency revealed through in vivo B cell knockout models
Cancers associated with the oncogenic gammaherpesviruses, Epstein-Barr virus and
Kaposi sarcoma herpesvirus, are notable for their constitutive activation of the transcription …
Kaposi sarcoma herpesvirus, are notable for their constitutive activation of the transcription …
B cell-intrinsic STAT3-mediated support of latency and interferon suppression during murine gammaherpesvirus 68 infection revealed through an in vivo competition …
CH Hogan, SM Owens, GV Reynoso, V Kirillov… - …, 2023 - pmc.ncbi.nlm.nih.gov
Cancers associated with the oncogenic gammaherpesviruses, Epstein-Barr virus and
Kaposi sarcoma herpesvirus, are notable for their constitutive activation of the transcription …
Kaposi sarcoma herpesvirus, are notable for their constitutive activation of the transcription …