Biology and medicine in the landscape of quantum advantages

BA Cordier, NPD Sawaya… - Journal of the …, 2022 - royalsocietypublishing.org
Quantum computing holds substantial potential for applications in biology and medicine,
spanning from the simulation of biomolecules to machine learning methods for subty** …

[HTML][HTML] Evolution of metastasis: new tools and insights

P Gui, TG Bivona - Trends in Cancer, 2022 - cell.com
Metastasis is an evolutionary process occurring across multiple organs and timescales. Due
to its continuous and dynamic nature, this multifaceted process has been challenging to …

Molecular biology and evolution of cancer: from discovery to action

JA Somarelli, H Gardner, VL Cannataro… - Molecular biology …, 2020 - academic.oup.com
Cancer progression is an evolutionary process. During this process, evolving cancer cell
populations encounter restrictive ecological niches within the body, such as the primary …

[HTML][HTML] The hallmarks of cancer as ecologically driven phenotypes

JA Somarelli - Frontiers in ecology and evolution, 2021 - frontiersin.org
Ecological fitness is the ability of individuals in a population to survive and reproduce.
Individuals with increased fitness are better equipped to withstand the selective pressures of …

Phylogenomics and the genetic architecture of the placental mammal radiation

WJ Murphy, NM Foley, KR Bredemeyer… - Annual Review of …, 2021 - annualreviews.org
The genomes of placental mammals are being sequenced at an unprecedented rate.
Alignments of hundreds, and one day thousands, of genomes spanning the rich living and …

A gene for all seasons: The evolutionary consequences of HIF-1 in carcinogenesis, tumor growth and metastasis

R Bhattacharya, JS Brown, RA Gatenby… - Seminars in Cancer …, 2024 - Elsevier
Oxygen played a pivotal role in the evolution of multicellularity during the Cambrian
Explosion. Not surprisingly, responses to fluctuating oxygen concentrations are integral to …

Phylogenetics algorithms and applications

G Munjal, M Hanmandlu, S Srivastava - Ambient Communications and …, 2019 - Springer
Phylogenetics is a powerful approach in finding evolution of current day species. By
studying phylogenetic trees, scientists gain a better understanding of how species have …

Neutral theory and the somatic evolution of cancer

VL Cannataro, JP Townsend - Molecular biology and evolution, 2018 - academic.oup.com
Kimura's neutral theory argued that positive selection was not responsible for an
appreciable fraction of molecular substitutions. Correspondingly, quantitative analysis …

Cancer phylogenetic inference using copy number alterations detected from DNA sequencing data

B Lu - Cancer pathogenesis and therapy, 2025 - mednexus.org
Cancer is an evolutionary process involving the accumulation of diverse somatic mutations
and clonal evolution over time. Phylogenetic inference from samples obtained from an …

J-SPACE: a Julia package for the simulation of spatial models of cancer evolution and of sequencing experiments

F Angaroni, A Guidi, G Ascolani, A d'Onofrio… - BMC …, 2022 - Springer
Background The combined effects of biological variability and measurement-related errors
on cancer sequencing data remain largely unexplored. However, the spatio-temporal …