Abstract Three-dimensional (3D) cell culture has tremendous advantages to closely mimic
the in vivo architecture and microenvironment of healthy tissue and organs, as well as of …

Abstract Inherited Retinal Diseases (IRDs) are considered one of the leading causes of
blindness worldwide. However, the majority of them still lack a safe and effective treatment …

Mesenchymal stem/progenitor cells (MSCs) are key players in regenerative medicine,
relying principally on their differentiation/regeneration potential, immunomodulatory …

The development of bioprocesses capable of producing large numbers of human induced
pluripotent stem cells (hiPSC) in a robust and safe manner is critical for the application of …

Human pluripotent stem cells (hPSC) have attracted a great attention as an unlimited source
of cells for cell therapies and other in vitro biomedical applications such as drug screening …

A low percentage of novel drug candidates succeed and reach the end of the drug discovery
pipeline, mainly due to poor initial screening and assessment of the effects of the drug and …

With the ever-increasing clinical application of cell-based therapies, it is considered critical
to develop systems that facilitate the storage and distribution of cell therapy products (CTPs) …

Diabetes medication is based on controlling blood glucose and delaying the onset of related
complications and is not a complete cure for diabetes. Conventional drug therapy fails to …

BACKGROUND Human induced pluripotent stem cells (hiPSC) are expected to become
powerful tools for disease modelling, for the discovery and testing of new drugs and …

BACKGROUND Human induced pluripotent stem (hiPS) cells provide a fascinating tool for
exploring disease mechanisms, compound screening in pharmaceutical drug development …