[HTML][HTML] Bioavailability enhancement techniques for poorly aqueous soluble drugs and therapeutics

DV Bhalani, B Nutan, A Kumar, AK Singh Chandel - Biomedicines, 2022 - mdpi.com
The low water solubility of pharmacoactive molecules limits their pharmacological potential,
but the solubility parameter cannot compromise, and so different approaches are employed …

Physicochemical and biopharmaceutical aspects influencing skin permeation and role of SLN and NLC for skin drug delivery

EB Souto, JF Fangueiro, AR Fernandes, A Cano… - Heliyon, 2022 - cell.com
The skin is a complex and multifunctional organ, in which the static versus dynamic balance
is responsible for its constant adaptation to variations in the external environment that is …

Solid lipid nanoparticles and nanostructured lipid carriers: A review emphasizing on particle structure and drug release

A Gordillo-Galeano, CE Mora-Huertas - European Journal of Pharmaceutics …, 2018 - Elsevier
Colloidal systems based on lipids have attracted attention during the last two decades as a
delivery method of drugs that are poorly soluble in water. The investigations carried out have …

SLN and NLC for topical, dermal, and transdermal drug delivery

EB Souto, I Baldim, WP Oliveira, R Rao… - Expert opinion on …, 2020 - Taylor & Francis
Introduction From a biopharmaceutical standpoint, the skin is recognized as an interesting
route for drug delivery. In general, small molecules are able to penetrate the stratum …

[HTML][HTML] Lipid nanoparticles as a promising drug delivery carrier for topical ocular therapy—an overview on recent advances

S Jacob, AB Nair, J Shah, S Gupta, SHS Boddu… - Pharmaceutics, 2022 - mdpi.com
Due to complicated anatomical and physical properties, targeted drug delivery to ocular
tissues continues to be a key challenge for formulation scientists. Various attempts are …

Optimization of nanostructured lipid carriers: Understanding the types, designs, and parameters in the process of formulations

B Subramaniam, ZH Siddik, NH Nagoor - Journal of nanoparticle research, 2020 - Springer
Lipid-based nanoparticles for drug delivery have been employed in the development of
nanomedicine for various applications. One such versatile nanoparticle type is …

Nanostructured lipid carriers (NLC): A potential delivery system for bioactive food molecules

F Tamjidi, M Shahedi, J Varshosaz… - Innovative Food Science & …, 2013 - Elsevier
Particle size and physical state of the lipid phase are major factors influencing the
permanence of lipid dispersions. Nanostructured lipid carriers (NLC) are a delivery system …

Current state‐of‐art and new trends on lipid nanoparticles (SLN and NLC) for oral drug delivery

P Severino, T Andreani, AS Macedo… - Journal of drug …, 2012 - Wiley Online Library
Lipids and lipid nanoparticles are extensively employed as oral‐delivery systems for drugs
and other active ingredients. These have been exploited for many features in the field of …

Polymeric and solid lipid nanoparticles for sustained release of carbendazim and tebuconazole in agricultural applications

EVR Campos, JL Oliveira, CMG da Silva, M Pascoli… - Scientific reports, 2015 - nature.com
Abstract Carbendazim (MBC)(methyl-2-benzimidazole carbamate) and tebuconazole
(TBZ)((RS)-1-(4-chlorophenyl)-4, 4-dimethyl-3-(1H-1, 2, 4-triazol-1-ylmethyl) pentan-3-ol) …

Solid lipid nanoparticles for encapsulation of hydrophilic drugs by an organic solvent free double emulsion technique

LB Peres, LB Peres, PHH de Araújo, C Sayer - Colloids and Surfaces B …, 2016 - Elsevier
Encapsulation of hydrophilic compounds for drug delivery systems with high loading
efficiency is not easily feasible and remains a challenge, mainly due to the leaking of the …