Systemic sclerosis (SSc), also referred to as systemic scleroderma or scleroderma, is a rare,
complex immune-mediated connective tissue disease characterized by progressive skin …

Systemic autoimmune rheumatic diseases (SARDs) exhibit extensive heterogeneity in
clinical presentation, disease course, and treatment response. Therefore, precision …

Objectives Recent advances in systemic sclerosis (SSc) show that it involves a T-helper type-
2-oriented immune response with interleukin (IL)-4 and IL-13. Romilkimab is an engineered …

Systemic sclerosis (SSc) is a rare multisystem autoimmune disease, characterized by
fibrosis, vasculopathy, and autoimmunity. Recent advances have highlighted the significant …

Abstract Background Systemic sclerosis (SSc) is a systemic autoimmune disease with
heterogeneous clinical presentation and prognosis. JAK inhibitors reduced cutaneous and …

Systemic sclerosis (SSc) is a connective tissue disease characterized by extensive fibrosis
of the skin and internal organs, associated with vasculopathy and autoimmune features …

This guideline was developed according to the British Society for Rheumatology Guidelines
Protocol by a Guideline Development Group comprising healthcare professionals with …

Objective To analyze the effectiveness and safety of intravenous immunoglobulin (IVIG)
given in routine care to patients with systemic sclerosis (SSc). Methods A retrospective …

ABSTRACT Introduction: Systemic sclerosis (SSc), also known as scleroderma, is a complex
orphan disease characterized by early inflammatory features, vascular hyper-reactivity, and …

Systemic sclerosis (SSc) is a heterogeneous multisystem autoimmune disease whereby its
main pathological drivers of disability and damage are vascular injury, inflammatory cell …