Mechanisms of disease: inflammatory bowel diseases

GP Ramos, KA Papadakis - Mayo Clinic Proceedings, 2019 - Elsevier
Inflammatory bowel diseases (IBDs), represented by Crohn disease and ulcerative colitis,
are associated with major morbidity in Western countries and with increasing incidence in …

Inflammatory bowel disease: tri-directional relationship between microbiota, immune system and intestinal epithelium

S Ahlawat, P Kumar, H Mohan, S Goyal… - Critical Reviews in …, 2021 - Taylor & Francis
Human gut microbiota contributes to host nutrition and metabolism, sustains intestinal cell
proliferation and differentiation, and modulates host immune system. The alterations in their …

A novel therapeutic approach for inflammatory bowel disease by exosomes derived from human umbilical cord mesenchymal stem cells to repair intestinal barrier via …

S Yang, X Liang, J Song, C Li, A Liu, Y Luo… - Stem cell research & …, 2021 - Springer
Background Exosomes as the main therapeutic vectors of mesenchymal stem cells (MSC)
for inflammatory bowel disease (IBD) treatment and its mechanism remain unexplored …

Adipose‐derived mesenchymal stem cell‐secreted exosome alleviates dextran sulfate sodium‐induced acute colitis by Treg cell induction and inflammatory cytokine …

N Heidari, H Abbasi‐Kenarsari… - Journal of cellular …, 2021 - Wiley Online Library
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is an
inflammatory condition that results in gastrointestinal tract damage. Various factors …

Identification and validation of multiple cell surface markers of clinical-grade adipose-derived mesenchymal stromal cells as novel release criteria for good …

ET Camilleri, MP Gustafson, A Dudakovic… - Stem cell research & …, 2016 - Springer
Background Clinical translation of mesenchymal stromal cells (MSCs) necessitates basic
characterization of the cell product since variability in biological source and processing of …

Mesenchymal stem cells against intestinal ischemia–reperfusion injury: a systematic review and meta-analysis of preclinical studies

Y Shi, X Zhang, Z Wan, X Liu, F Chen, J Zhang… - Stem Cell Research & …, 2022 - Springer
Background Intestinal ischemia–reperfusion injury (IRI) causes localized and distant tissue
lesions. Multiple organ failure is a common complication of severe intestinal IRI, leading to …

Mesenchymal stem cells: from identification and characterization to clinical applications

M Alvarez-Viejo, KH Haider - Handbook of stem cell therapy, 2022 - Springer
Since Friedenstein and co-workers first reported bone marrow-derived mesenchymal stem
cells (MSCs) during the early 1970s, several researchers have focused on their biology and …

[HTML][HTML] Inflammatory bowel disease and its treatment in 2018: Global and Taiwanese status updates

HJ Su, YT Chiu, CT Chiu, YC Lin, CY Wang… - Journal of the Formosan …, 2019 - Elsevier
The global incidence and prevalence of inflammatory bowel disease (IBD) has increased
over the last 2-4 decades, likely because of the adoption of a more “western” lifestyle as well …

Therapeutic applications of mesenchymal stem cells in idiopathic pulmonary fibrosis

S Yang, P Liu, Y Jiang, Z Wang, H Dai… - Frontiers in Cell and …, 2021 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is an interstitial disease of unknown etiology
characterized by progressive pulmonary fibrosis. Pirfenidone and nintedanib are the only …

Efficacy and safety of mesenchymal stem/stromal cell therapy for inflammatory bowel diseases: an up-to-date systematic review

JZH Ko, S Johnson, M Dave - Biomolecules, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gut that can lead
to severe gastrointestinal symptoms, malnutrition, and complications such as fistulas and …