[HTML][HTML] Interactome networks and human disease
Complex biological systems and cellular networks may underlie most genotype to
phenotype relationships. Here, we review basic concepts in network biology, discussing …
phenotype relationships. Here, we review basic concepts in network biology, discussing …
Cis-regulatory elements: molecular mechanisms and evolutionary processes underlying divergence
Cis-regulatory sequences, such as enhancers and promoters, control development and
physiology by regulating gene expression. Mutations that affect the function of these …
physiology by regulating gene expression. Mutations that affect the function of these …
Recombinational cloning with plant gateway vectors
M Karimi, A Depicker, P Hilson - Plant physiology, 2007 - academic.oup.com
The study of biological systems relies to a large extent on DNA cloning technologies
enabling the analysis of recombinant genes through transgenic research. In this context, the …
enabling the analysis of recombinant genes through transgenic research. In this context, the …
Mutation of a bHLH transcription factor allowed almond domestication
Wild almond species accumulate the bitter and toxic cyanogenic diglucoside amygdalin.
Almond domestication was enabled by the selection of genotypes harboring sweet kernels …
Almond domestication was enabled by the selection of genotypes harboring sweet kernels …
Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis
P Gasch, M Fundinger, JT Müller, T Lee… - The Plant …, 2016 - academic.oup.com
The response of Arabidopsis thaliana to low-oxygen stress (hypoxia), such as during shoot
submergence or root waterlogging, includes increasing the levels of∼ 50 hypoxia …
submergence or root waterlogging, includes increasing the levels of∼ 50 hypoxia …
Gene regulatory networks and the role of robustness and stochasticity in the control of gene expression
In any given cell, thousands of genes are expressed and work in concert to ensure the cell's
function, fitness, and survival. Each gene, in turn, must be expressed at the proper time and …
function, fitness, and survival. Each gene, in turn, must be expressed at the proper time and …
[HTML][HTML] Profiling the human protein-DNA interactome reveals ERK2 as a transcriptional repressor of interferon signaling
S Hu, Z ** of the HY5‐mediated genenetworks in Arabidopsis that involve both transcriptional and post‐transcriptional regulation
Summary LONG HYPOCOTYL 5 (HY5) is a basic leucine zipper transcription factor (TF) that
functions downstream of multiple families of photoreceptors. Mutations in the HY5 gene …
functions downstream of multiple families of photoreceptors. Mutations in the HY5 gene …
Gateway compatible vectors for analysis of gene function in the zebrafish
JA Villefranc, J Amigo… - … dynamics: an official …, 2007 - Wiley Online Library
The recent establishment of recombination‐based cloning systems has greatly facilitated the
analysis of gene function by allowing rapid and high‐efficiency generation of plasmid …
analysis of gene function by allowing rapid and high‐efficiency generation of plasmid …
Functional analysis of transcription factors in Arabidopsis
Transcription factors (TFs) regulate the expression of genes at the transcriptional level.
Modification of TF activity dynamically alters the transcriptome, which leads to metabolic and …
Modification of TF activity dynamically alters the transcriptome, which leads to metabolic and …