Pioneering work by, among others, the groups of Hunt and Mann at the start of this century
opened up the era of mass spectrometry (MS)-based phosphoproteomics. 1− 3 Through …

Reversible phosphorylation is the most widespread posttranslational protein modification,
playing regulatory role in almost every aspect of cell life. The majority of protein …

The complexity of higher organisms is not simply a reflection of the number of genes. A
network of additional regulatory features, including protein post-translational modifications …

Protein kinases are fascinating biological catalysts with a rapidly expanding knowledge
base, a growing appreciation in cell regulatory control, and an ascendant role in successful …

Nanodiamonds (NDs) are considered to be relatively safe carbon nanomaterials used for
the transmission of DNA, proteins and drugs. The feasibility of utilizing the NDs to deliver …

Protein phosphorylation controls major processes in cells. Although phosphorylation of
serine, threonine, and tyrosine and also recently histidine and arginine are well-established …

In recent years, labile phosphorylation sites on arginine, histidine, cysteine, and lysine as
well as pyrophosphorylation of serine and threonine have gained more attention in …

There is growing evidence to suggest that phosphohistidines are present at significant levels
in mammalian cells and play a part in regulating cellular activity, in particular signaling …

Due to its key roles in regulating the occurrence and development of cancer, protein
histidine phosphorylation has been increasingly recognized as an important form of post …

Protein arginine phosphorylation is a recently discovered modification that affects multiple
cellular pathways in Gram-positive bacteria. In particular, the phosphorylation of arginine …