The autonomic nervous system and heart failure

VG Florea, JN Cohn - Circulation research, 2014 - ahajournals.org
The pathophysiology of heart failure (HF) is characterized by hemodynamic abnormalities
that result in neurohormonal activation and autonomic imbalance with increase in …

Autonomic nervous system and immune system interactions

MJ Kenney, CK Ganta - Comprehensive physiology, 2014 - pmc.ncbi.nlm.nih.gov
The present review assesses the current state of literature defining integrative autonomic-
immune physiological processing, focusing on studies that have employed …

Vagally mediated heart rate recovery after exercise is accelerated in athletes but blunted in patients with chronic heart failure

K Imai, H Sato, M Hori, H Kusuoka, H Ozaki… - Journal of the American …, 1994 - Elsevier
Objectives. Vagally mediated heart rate recovery after exercise was assessed in patients
with chronic heart failure and in well trained athletes by analyzing the postexercise heart …

[HTML][HTML] Exercise training-induced modification in autonomic nervous system: An update for cardiac patients

F Besnier, M Labrunee, A Pathak… - Annals of physical and …, 2017 - Elsevier
Patients with cardiovascular disease show autonomic dysfunction, including sympathetic
activation and vagal withdrawal, which leads to fatal events. This review aims to place …

Arterial baroreflex modulation of heart rate in chronic heart failure: clinical and hemodynamic correlates and prognostic implications

A Mortara, MT La Rovere, GD Pinna, A Prpa… - Circulation, 1997 - ahajournals.org
Background In chronic heart failure (CHF), arterial baroreflex regulation of cardiac function is
impaired, leading to a reduction in the tonic restraining influence on the sympathetic nervous …

Digoxin in the management of cardiovascular disorders

M Gheorghiade, KF Adams Jr, WS Colucci - Circulation, 2004 - ahajournals.org
(1) Baroreceptor function: In lowoutput HF models, there is attenuation of carotid sinus
baroreceptor discharge sensitivity. Administration of digoxin produces improvement in …

Clinical aspects of sympathetic activation and parasympathetic withdrawal in heart failure

JS Floras - Journal of the American College of Cardiology, 1993 - Elsevier
Proposed reflex mechanisms for generalized neurohumoral activation in heart failure
include decreased input from inhibitory baroreceptor afferent vessels and increased input …

Development, maturation, and transdifferentiation of cardiac sympathetic nerves

K Kimura, M Ieda, K Fukuda - Circulation research, 2012 - ahajournals.org
The heart is electrically and mechanically controlled as a syncytium by the autonomic
nervous system. The cardiac nervous system comprises the sympathetic, parasympathetic …

Neuroendocrine activation in heart failure is modified by endurance exercise training

RW Braith, MA Welsch, MS Feigenbaum… - Journal of the American …, 1999 - jacc.org
OBJECTIVES The purpose of this study was to determine whether endurance exercise
training could buffer neuroendocrine activity in chronic heart failure patients …

Digoxin

EJ Eichhorn, M Gheorghiade - Progress in cardiovascular diseases, 2002 - Elsevier
After 200 years of use, digitalis still appears to have a place in our armamentarium for heart
failure and atrial fibrillation despite the proven survival benefits with ACE inhibitors and β …