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Chemical Biology of H2S Signaling through Persulfidation
Signaling by H2S is proposed to occur via persulfidation, a posttranslational modification of
cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for …
cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for …
Biogenesis of reactive sulfur species for signaling by hydrogen sulfide oxidation pathways
The chemical species involved in H2S signaling remain elusive despite the profound and
pleiotropic physiological effects elicited by this molecule. The dominant candidate …
pleiotropic physiological effects elicited by this molecule. The dominant candidate …
Redox chemistry and chemical biology of H2S, hydropersulfides, and derived species: implications of their possible biological activity and utility
K Ono, T Akaike, T Sawa, Y Kumagai, DA Wink… - Free Radical Biology …, 2014 - Elsevier
Hydrogen sulfide (H 2 S) is an endogenously generated and putative signaling/effector
molecule. Despite its numerous reported functions, the chemistry by which it elicits its …
molecule. Despite its numerous reported functions, the chemistry by which it elicits its …
Redox biochemistry of hydrogen sulfide
H 2 S, the most recently discovered gasotransmitter, might in fact be the evolutionary
matriarch of this family, being both ancient and highly reduced. Disruption of γ-cystathionase …
matriarch of this family, being both ancient and highly reduced. Disruption of γ-cystathionase …
C–H⋯ S hydrogen bonding interactions
The short C–H⋯ S contacts found in available structural data for both small molecules and
larger biomolecular systems suggest that such contacts are an often overlooked yet …
larger biomolecular systems suggest that such contacts are an often overlooked yet …
[HTML][HTML] Chemical foundations of hydrogen sulfide biology
Q Li, JR Lancaster Jr - Nitric oxide, 2013 - Elsevier
Following nitric oxide (nitrogen monoxide) and carbon monoxide, hydrogen sulfide (or its
newer systematic name sulfane, H 2 S) became the third small molecule that can be both …
newer systematic name sulfane, H 2 S) became the third small molecule that can be both …
Hydrogen sulfide: an emerging precision strategy for gas therapy
H Ding, J Chang, F He, S Gai… - Advanced Healthcare …, 2022 - Wiley Online Library
Advances in nanotechnology have enabled the rapid development of stimuli‐responsive
therapeutic nanomaterials for precision gas therapy. Hydrogen sulfide (H2S) is a significant …
therapeutic nanomaterials for precision gas therapy. Hydrogen sulfide (H2S) is a significant …
Measurement of plasma hydrogen sulfide in vivo and in vitro
The gasotransmitter hydrogen sulfide is known to regulate multiple cellular functions during
normal and pathophysiological states. However, a paucity of concise information exists …
normal and pathophysiological states. However, a paucity of concise information exists …
H2S and its role in redox signaling
Hydrogen sulfide (H 2 S) has emerged as an important gaseous signaling molecule that is
produced endogenously by enzymes in the sulfur metabolic network. H 2 S exerts its effects …
produced endogenously by enzymes in the sulfur metabolic network. H 2 S exerts its effects …
[HTML][HTML] Interactions of reactive sulfur species with metalloproteins
Reactive sulfur species (RSS) entail a diverse family of sulfur derivatives that have emerged
as important effector molecules in H 2 S-mediated biological events. RSS (including H 2 S) …
as important effector molecules in H 2 S-mediated biological events. RSS (including H 2 S) …