Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …
Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter
Hydrogen sulfide (H2S) has become recognized as an important signalling molecule
throughout the body, contributing to many physiological and pathological processes. In …
throughout the body, contributing to many physiological and pathological processes. In …
Physiological implications of hydrogen sulfide: a whiff exploration that blossomed
R Wang - Physiological reviews, 2012 - journals.physiology.org
The important life-supporting role of hydrogen sulfide (H2S) has evolved from bacteria to
plants, invertebrates, vertebrates, and finally to mammals. Over the centuries, however, H2S …
plants, invertebrates, vertebrates, and finally to mammals. Over the centuries, however, H2S …
Cystathionine-β-synthase: molecular regulation and pharmacological inhibition
Cystathionine-β-synthase (CBS), the first (and rate-limiting) enzyme in the transsulfuration
pathway, is an important mammalian enzyme in health and disease. Its biochemical …
pathway, is an important mammalian enzyme in health and disease. Its biochemical …
Sulfur amino acid metabolism: pathways for production and removal of homocysteine and cysteine
MH Stipanuk - Annu. Rev. Nutr., 2004 - annualreviews.org
▪ Abstract Tissue concentrations of both homocysteine (Hcy) and cysteine (Cys) are
maintained at low levels by regulated production and efficient removal of these thiols. The …
maintained at low levels by regulated production and efficient removal of these thiols. The …
Progress and perspective on hydrogen sulfide donors and their biomedical applications
ZL Song, L Zhao, T Ma, A Osama… - Medicinal Research …, 2022 - Wiley Online Library
Following the discovery of nitric oxide (NO) and carbon monoxide (CO), hydrogen sulfide
(H2S) has been identified as the third gasotransmitter in humans. Increasing evidence have …
(H2S) has been identified as the third gasotransmitter in humans. Increasing evidence have …
Hydrogen sulfide and cellular redox homeostasis
Intracellular redox imbalance is mainly caused by overproduction of reactive oxygen species
(ROS) or weakness of the natural antioxidant defense system. It is involved in the …
(ROS) or weakness of the natural antioxidant defense system. It is involved in the …
Emerging role of hydrogen sulfide in health and disease: critical appraisal of biomarkers and pharmacological tools
M Whiteman, S Le Trionnaire, M Chopra, B Fox… - Clinical …, 2011 - portlandpress.com
H2S (hydrogen sulfide) is a well known and pungent gas recently discovered to be
synthesized enzymatically in mammalian and human tissues. In a relatively short period of …
synthesized enzymatically in mammalian and human tissues. In a relatively short period of …
Measurement of plasma hydrogen sulfide in vivo and in vitro
The gasotransmitter hydrogen sulfide is known to regulate multiple cellular functions during
normal and pathophysiological states. However, a paucity of concise information exists …
normal and pathophysiological states. However, a paucity of concise information exists …
[HTML][HTML] Surface-fill H2S-releasing silk fibroin hydrogel for brain repair through the repression of neuronal pyroptosis
X Chen, X Huang, C Liu, S Li, Z Yang, F Zhang… - Acta Biomaterialia, 2022 - Elsevier
Traumatic brain injury (TBI) remains the major cause of disability and mortality worldwide
due to the persistent neuroinflammation and neuronal death induced by TBI. Among them …
due to the persistent neuroinflammation and neuronal death induced by TBI. Among them …