Therapies for delayed cerebral ischemia in aneurysmal subarachnoid hemorrhage

VA Shah, LF Gonzalez, JI Suarez - Neurocritical care, 2023 - Springer
Delayed cerebral ischemia (DCI) is one of the most important complications of subarachnoid
hemorrhage. Despite lack of prospective evidence, medical rescue interventions for DCI …

Beyond nimodipine: advanced neuroprotection strategies for aneurysmal subarachnoid hemorrhage vasospasm and delayed cerebral ischemia

S Luzzi, PK Bektaşoğlu, Y Doğruel, A Güngor - Neurosurgical review, 2024 - Springer
The clinical management of aneurysmal subarachnoid hemorrhage (SAH)-associated
vasospasm remains a challenge in neurosurgical practice, with its prevention and treatment …

Endovascular treatment of cerebral vasospasm after subarachnoid hemorrhage: more is more

R Jabbarli, D Pierscianek, R Rölz, M Darkwah Oppong… - Neurology, 2019 - neurology.org
Objective Delayed cerebral ischemia (DCI) is strongly associated with poor outcome after
subarachnoid hemorrhage (SAH). Cerebral vasospasm is a major contributor to DCI and …

Detection of delayed cerebral ischemia using objective pupillometry in patients with aneurysmal subarachnoid hemorrhage

SG Aoun, SE Stutzman, PUN Vo, TY El Ahmadieh… - Journal of …, 2019 - thejns.org
OBJECTIVE Cerebral vasospasm causing delayed cerebral ischemia (DCI) is a source of
significant morbidity after subarachnoid hemorrhage (SAH). Transcranial Doppler is used at …

C-reactive protein/albumin ratio correlates with disease severity and predicts outcome in patients with aneurysmal subarachnoid hemorrhage

D Zhang, H Yan, Y Wei, X Liu, Z Zhuang, W Dai… - Frontiers in …, 2019 - frontiersin.org
Aim: The purpose of the present study was to determine if C-reactive protein (CRP)/albumin
ratio was associated with disease severity and unfavorable outcome in patients with …

Medical treatment failure for symptomatic vasospasm after subarachnoid hemorrhage threatens long-term outcome

S Suwatcharangkoon, GM De Marchis, J Witsch… - Stroke, 2019 - ahajournals.org
Background and Purpose—Symptomatic vasospasm is a common cause of morbidity and
mortality after subarachnoid hemorrhage. We sought to identify predictors and the long-term …

[HTML][HTML] Nimodipine-dependent protection of schwann cells, astrocytes and neuronal cells from osmotic, oxidative and heat stress is associated with the activation of …

S Leisz, S Simmermacher, J Prell, C Strauss… - International Journal of …, 2019 - mdpi.com
Clinical and experimental data assumed a neuroprotective effect of the calcium channel
blocker nimodipine. However, it has not been proven which neuronal or glial cell types are …

Update on intrathecal management of cerebral vasospasm: a systematic review and meta-analysis

AA Grossen, GL Ernst, AM Bauer - Neurosurgical Focus, 2022 - thejns.org
OBJECTIVE Aneurysmal subarachnoid hemorrhage (aSAH) accounts for a relatively small
portion of strokes but has the potential to cause permanent neurological deficits. Vasospasm …

Neutrophil-to-albumin ratio as a biomarker of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage

X Zhang, Y Liu, S Zhang, C Wang, C Zou, A Li - World Neurosurgery, 2021 - Elsevier
Objective This study set out to investigate the relationships between the neutrophil-to-
albumin ratio (NAR) in the early stages of aneurysmal subarachnoid hemorrhage (aSAH) …

Inhaled nitric oxide treatment for aneurysmal SAH patients with delayed cerebral ischemia

C Fung, WJ Z'Graggen, SM Jakob, J Gralla… - Frontiers in …, 2022 - frontiersin.org
Background We demonstrated experimentally that inhaled nitric oxide (iNO) dilates
hypoperfused arterioles, increases tissue perfusion, and improves neurological outcome …