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Mechanism of deep brain stimulation: inhibition, excitation, or disruption?
S Chiken, A Nambu - The neuroscientist, 2016 - journals.sagepub.com
Deep brain stimulation (DBS), applying high-frequency electrical stimulation to deep brain
structures, has now provided an effective therapeutic option for treatment of various …
structures, has now provided an effective therapeutic option for treatment of various …
Network perspectives on the mechanisms of deep brain stimulation
CC McIntyre, PJ Hahn - Neurobiology of disease, 2010 - Elsevier
Deep brain stimulation (DBS) is an established medical therapy for the treatment of
movement disorders and shows great promise for several other neurological disorders …
movement disorders and shows great promise for several other neurological disorders …
An optical neural interface: in vivo control of rodent motor cortex with integrated fiberoptic and optogenetic technology
Neural interface technology has made enormous strides in recent years but stimulating
electrodes remain incapable of reliably targeting specific cell types (eg excitatory or …
electrodes remain incapable of reliably targeting specific cell types (eg excitatory or …
Alterations in neuronal activity in basal ganglia-thalamocortical circuits in the parkinsonian state
A Galvan, A Devergnas, T Wichmann - Frontiers in neuroanatomy, 2015 - frontiersin.org
In patients with Parkinson's disease and in animal models of this disorder, neurons in the
basal ganglia and related regions in thalamus and cortex show changes that can be …
basal ganglia and related regions in thalamus and cortex show changes that can be …
The aperiodic exponent of subthalamic field potentials reflects excitation/inhibition balance in Parkinsonism
Periodic features of neural time-series data, such as local field potentials (LFPs), are often
quantified using power spectra. While the aperiodic exponent of spectra is typically …
quantified using power spectra. While the aperiodic exponent of spectra is typically …
[HTML][HTML] Mechanisms and targets of deep brain stimulation in movement disorders
Chronic electrical stimulation of the brain, known as deep brain stimulation (DBS), has
become a preferred surgical treatment for medication-refractory movement disorders …
become a preferred surgical treatment for medication-refractory movement disorders …
Frequency-specific optogenetic deep brain stimulation of subthalamic nucleus improves parkinsonian motor behaviors
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective therapy for the
motor symptoms of Parkinson's disease (PD). However, the neural elements mediating …
motor symptoms of Parkinson's disease (PD). However, the neural elements mediating …
Resonant antidromic cortical circuit activation as a consequence of high-frequency subthalamic deep-brain stimulation
S Li, GW Arbuthnott, MJ Jutras… - Journal of …, 2007 - journals.physiology.org
Deep brain stimulation (DBS) is an effective treatment of Parkinson's disease (PD) for many
patients. The most effective stimulation consists of high-frequency biphasic stimulation …
patients. The most effective stimulation consists of high-frequency biphasic stimulation …
Effective deep brain stimulation suppresses low-frequency network oscillations in the basal ganglia by regularizing neural firing patterns
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective treatment for
the motor symptoms of Parkinson's disease (PD). The effects of DBS depend strongly on …
the motor symptoms of Parkinson's disease (PD). The effects of DBS depend strongly on …
Deep brain stimulation mechanisms: beyond the concept of local functional inhibition
JM Deniau, B Degos, C Bosch… - European Journal of …, 2010 - Wiley Online Library
Deep brain electrical stimulation has become a recognized therapy in the treatment of a
variety of motor disorders and has potentially promising applications in a wide range of …
variety of motor disorders and has potentially promising applications in a wide range of …