Anticancer Diterpenes of African Natural Products: Mechanistic Pathways and Preclinical Developments

G Bangay, FZ Brauning, A Rosatella, AM Díaz-Lanza… - Phytomedicine, 2024 - Elsevier
ABSTRACT Background The African continent is home to five biodiversity hotspots, boasting
an immense wealth of medicinal flora, fungi and marine life. Diterpenes extracted from such …

Anti-inflammatory and cytotoxic activities of clerodane-type diterpenes

RM Martínez-Casares, L Hernández-Vázquez… - Molecules, 2023 - mdpi.com
The secondary metabolites of clerodane diterpenoids have been found in several plant
species from various families and in other organisms. In this review, we included articles on …

Investigation of the effects of Theranekron and Sorafenib treatments on carcinogenesis, apoptosis and biochemical profile in hepatocellular carcinoma in rats

S Vanli, F Kurtoglu, BS Alan, G Akcakavak… - Toxicology …, 2024 - Taylor & Francis
This study aimed to investigate the effects of Tarantula cubensis alcohol extract (TCAE,
Theranekron) and Sorafenib (S) treatments on carcinogenesis, apoptosis and biochemical …

Propofol Suppresses Glioma Oncogenic Phenotypes via the SET Binding Factor 2-Antisense Strand 1/microRNA-373-3p/Pyruvate Dehydrogenase Kinase 3 Signaling …

L Jiang, H Cao, M Yu - Indian Journal of Pharmaceutical …, 2023 - search.ebscohost.com
Propofol, an anesthetic agent with known anticancer properties in various tumor types, holds
promise as a potential therapeutic option for glioma. However, the specific functions and …