The widespread regulation of microRNA biogenesis, function and decay

J Krol, I Loedige, W Filipowicz - Nature reviews genetics, 2010 - nature.com
MicroRNAs (miRNAs) are a large family of post-transcriptional regulators of gene expression
that are∼ 21 nucleotides in length and control many developmental and cellular processes …

Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy

MJ Millan, Y Agid, M Brüne, ET Bullmore… - Nature reviews Drug …, 2012 - nature.com
Studies of psychiatric disorders have traditionally focused on emotional symptoms such as
depression, anxiety and hallucinations. However, poorly controlled cognitive deficits are …

Inhibition of microRNA function by antimiR oligonucleotides

J Stenvang, A Petri, M Lindow, S Obad, S Kauppinen - Silence, 2012 - Springer
MicroRNAs (miRNAs) have emerged as important post-transcriptional regulators of gene
expression in many developmental and cellular processes. Moreover, there is now ample …

Determining the role of microRNAs in psychiatric disorders

O Issler, A Chen - Nature Reviews Neuroscience, 2015 - nature.com
Recent studies have revealed that patients with psychiatric disorders have altered
microRNA (miRNA) expression profiles in the circulation and brain. Furthermore, animal …

Circulating miRNA biomarkers for Alzheimer's disease

P Kumar, Z Dezso, C MacKenzie, J Oestreicher… - PloS one, 2013 - journals.plos.org
A minimally invasive diagnostic assay for early detection of Alzheimer's disease (AD) is
required to select optimal patient groups in clinical trials, monitor disease progression and …

Dicer1 and miR-219 Are required for normal oligodendrocyte differentiation and myelination

JC Dugas, TL Cuellar, A Scholze, B Ason, A Ibrahim… - Neuron, 2010 - cell.com
To investigate the role of microRNAs in regulating oligodendrocyte (OL) differentiation and
myelination, we utilized transgenic mice in which microRNA processing was disrupted in OL …

MicroRNAs in neuronal function and dysfunction

HI Im, PJ Kenny - Trends in neurosciences, 2012 - cell.com
MicroRNAs (miRNAs) are small noncoding RNA transcripts expressed throughout the brain
that can regulate neuronal gene expression at the post-transcriptional level. Here, we …

MicroRNA 135 is essential for chronic stress resiliency, antidepressant efficacy, and intact serotonergic activity

O Issler, S Haramati, ED Paul, H Maeno, I Navon… - Neuron, 2014 - cell.com
The link between dysregulated serotonergic activity and depression and anxiety disorders is
well established, yet the molecular mechanisms underlying these psychopathologies are not …

microRNAs at the synapse

G Schratt - Nature Reviews Neuroscience, 2009 - nature.com
MicroRNAs (miRNAs) are emerging as key modulators of post-transcriptional gene
regulation in a plethora of tissues, including the nervous system. Recent evidence points to …

[HTML][HTML] MicroRNA-mediated control of oligodendrocyte differentiation

X Zhao, X He, X Han, Y Yu, F Ye, Y Chen, TN Hoang… - Neuron, 2010 - cell.com
MicroRNAs (miRNAs) regulate various biological processes, but evidence for miRNAs that
control the differentiation program of specific neural cell types has been elusive. To …