The widespread regulation of microRNA biogenesis, function and decay
J Krol, I Loedige, W Filipowicz - Nature reviews genetics, 2010 - nature.com
MicroRNAs (miRNAs) are a large family of post-transcriptional regulators of gene expression
that are∼ 21 nucleotides in length and control many developmental and cellular processes …
that are∼ 21 nucleotides in length and control many developmental and cellular processes …
Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy
MJ Millan, Y Agid, M Brüne, ET Bullmore… - Nature reviews Drug …, 2012 - nature.com
Studies of psychiatric disorders have traditionally focused on emotional symptoms such as
depression, anxiety and hallucinations. However, poorly controlled cognitive deficits are …
depression, anxiety and hallucinations. However, poorly controlled cognitive deficits are …
Inhibition of microRNA function by antimiR oligonucleotides
MicroRNAs (miRNAs) have emerged as important post-transcriptional regulators of gene
expression in many developmental and cellular processes. Moreover, there is now ample …
expression in many developmental and cellular processes. Moreover, there is now ample …
Determining the role of microRNAs in psychiatric disorders
Recent studies have revealed that patients with psychiatric disorders have altered
microRNA (miRNA) expression profiles in the circulation and brain. Furthermore, animal …
microRNA (miRNA) expression profiles in the circulation and brain. Furthermore, animal …
Circulating miRNA biomarkers for Alzheimer's disease
P Kumar, Z Dezso, C MacKenzie, J Oestreicher… - PloS one, 2013 - journals.plos.org
A minimally invasive diagnostic assay for early detection of Alzheimer's disease (AD) is
required to select optimal patient groups in clinical trials, monitor disease progression and …
required to select optimal patient groups in clinical trials, monitor disease progression and …
Dicer1 and miR-219 Are required for normal oligodendrocyte differentiation and myelination
JC Dugas, TL Cuellar, A Scholze, B Ason, A Ibrahim… - Neuron, 2010 - cell.com
To investigate the role of microRNAs in regulating oligodendrocyte (OL) differentiation and
myelination, we utilized transgenic mice in which microRNA processing was disrupted in OL …
myelination, we utilized transgenic mice in which microRNA processing was disrupted in OL …
MicroRNAs in neuronal function and dysfunction
MicroRNAs (miRNAs) are small noncoding RNA transcripts expressed throughout the brain
that can regulate neuronal gene expression at the post-transcriptional level. Here, we …
that can regulate neuronal gene expression at the post-transcriptional level. Here, we …
MicroRNA 135 is essential for chronic stress resiliency, antidepressant efficacy, and intact serotonergic activity
The link between dysregulated serotonergic activity and depression and anxiety disorders is
well established, yet the molecular mechanisms underlying these psychopathologies are not …
well established, yet the molecular mechanisms underlying these psychopathologies are not …
microRNAs at the synapse
G Schratt - Nature Reviews Neuroscience, 2009 - nature.com
MicroRNAs (miRNAs) are emerging as key modulators of post-transcriptional gene
regulation in a plethora of tissues, including the nervous system. Recent evidence points to …
regulation in a plethora of tissues, including the nervous system. Recent evidence points to …
[HTML][HTML] MicroRNA-mediated control of oligodendrocyte differentiation
MicroRNAs (miRNAs) regulate various biological processes, but evidence for miRNAs that
control the differentiation program of specific neural cell types has been elusive. To …
control the differentiation program of specific neural cell types has been elusive. To …