[HTML][HTML] SARS-CoV-2 variant biology: immune escape, transmission and fitness
In late 2020, after circulating for almost a year in the human population, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …
SARS-CoV-2 evolution in the Omicron era
Abstract Since SARS-CoV-2 BA. 5 (Omicron) emerged and spread in 2022, Omicron
lineages have markedly diversified. Here we review the evolutionary trajectories and …
lineages have markedly diversified. Here we review the evolutionary trajectories and …
Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution
Continuous evolution of Omicron has led to a rapid and simultaneous emergence of
numerous variants that display growth advantages over BA. 5 (ref.). Despite their divergent …
numerous variants that display growth advantages over BA. 5 (ref.). Despite their divergent …
Immune boosting by B. 1.1. 529 (Omicron) depends on previous SARS-CoV-2 exposure
The Omicron, or Pango lineage B. 1.1. 529, variant of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) carries multiple spike mutations with high transmissibility and …
coronavirus 2 (SARS-CoV-2) carries multiple spike mutations with high transmissibility and …
[HTML][HTML] SARS-CoV-2 Omicron variant: recent progress and future perspectives
Since the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, there have been
a few variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), one of …
a few variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), one of …
Evolution and neutralization escape of the SARS-CoV-2 BA. 2.86 subvariant
Abstract Omicron BA. 2.86 subvariant differs from Omicron BA. 2 as well as recently
circulating variants by over 30 mutations in the spike protein alone. Here we report on the …
circulating variants by over 30 mutations in the spike protein alone. Here we report on the …
Resistance of Omicron subvariants BA. 2.75. 2, BA. 4.6, and BQ. 1.1 to neutralizing antibodies
Convergent evolution of SARS-CoV-2 Omicron BA. 2, BA. 4, and BA. 5 lineages has led to
the emergence of several new subvariants, including BA. 2.75. 2, BA. 4.6. and BQ. 1.1. The …
the emergence of several new subvariants, including BA. 2.75. 2, BA. 4.6. and BQ. 1.1. The …
Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently emerged
pathogenic human coronavirus that belongs to the sarbecovirus lineage of the genus …
pathogenic human coronavirus that belongs to the sarbecovirus lineage of the genus …
Neutralization, effector function and immune imprinting of Omicron variants
Currently circulating SARS-CoV-2 variants have acquired convergent mutations at hot spots
in the receptor-binding domain (RBD) of the spike protein. The effects of these mutations on …
in the receptor-binding domain (RBD) of the spike protein. The effects of these mutations on …
Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies
Abstract The SARS-CoV-2 B. 1.1. 529 (Omicron) variant contains 15 mutations of the
receptor-binding domain (RBD). How Omicron evades RBD-targeted neutralizing antibodies …
receptor-binding domain (RBD). How Omicron evades RBD-targeted neutralizing antibodies …