New insights into acute pancreatitis
The incidence of acute pancreatitis continues to increase worldwide, and it is one of the
most common gastrointestinal causes for hospital admission in the USA. In the past decade …
most common gastrointestinal causes for hospital admission in the USA. In the past decade …
Role of CFTR in epithelial physiology
Salt and fluid absorption and secretion are two processes that are fundamental to epithelial
function and whole body fluid homeostasis, and as such are tightly regulated in epithelial …
function and whole body fluid homeostasis, and as such are tightly regulated in epithelial …
The roles of calcium and ATP in the physiology and pathology of the exocrine pancreas
This review deals with the roles of calcium ions and ATP in the control of the normal
functions of the different cell types in the exocrine pancreas as well as the roles of these …
functions of the different cell types in the exocrine pancreas as well as the roles of these …
Guts and gall: bile acids in regulation of intestinal epithelial function in health and disease
Epithelial cells line the entire surface of the gastrointestinal tract and its accessory organs
where they primarily function in transporting digestive enzymes, nutrients, electrolytes, and …
where they primarily function in transporting digestive enzymes, nutrients, electrolytes, and …
Acute pancreatitis: a multifaceted set of organelle and cellular interactions
Acute pancreatitis is an inflammatory disorder of the exocrine pancreas associated with
tissue injury and necrosis. The disease can be mild, involving only the pancreas, and …
tissue injury and necrosis. The disease can be mild, involving only the pancreas, and …
Molecular Mechanism of Pancreatic and Salivary Gland Fluid and HCO3− Secretion
Fluid and HCO3− secretion is a vital function of all epithelia and is required for the survival of
the tissue. Aberrant fluid and HCO3− secretion is associated with many epithelial diseases …
the tissue. Aberrant fluid and HCO3− secretion is associated with many epithelial diseases …
Multifactorial scores and biomarkers of prognosis of acute pancreatitis: applications to research and practice
Acute pancreatitis (AP) is a severe inflammation of the pancreas presented with sudden
onset and severe abdominal pain with a high morbidity and mortality rate, if accompanied by …
onset and severe abdominal pain with a high morbidity and mortality rate, if accompanied by …
[HTML][HTML] Alcohol disrupts levels and function of the cystic fibrosis transmembrane conductance regulator to promote development of pancreatitis
Background & Aims Excessive consumption of ethanol is one of the most common causes of
acute and chronic pancreatitis. Alterations to the gene encoding the cystic fibrosis …
acute and chronic pancreatitis. Alterations to the gene encoding the cystic fibrosis …
Biology of pancreatic stellate cells—more than just pancreatic cancer
PE Ferdek, MA Jakubowska - Pflügers Archiv-European Journal of …, 2017 - Springer
Pancreatic stellate cells, normally quiescent, are capable of remarkable transition into their
activated myofibroblast-like phenotype. It is now commonly accepted that these cells play a …
activated myofibroblast-like phenotype. It is now commonly accepted that these cells play a …
Pathogenic mechanisms of acute pancreatitis
New findings necessitate a paradigm shift in our understanding of acute pancreatitis. Intra-
acinar trypsinogen activation leads to early pancreatic injury, but the inflammatory response …
acinar trypsinogen activation leads to early pancreatic injury, but the inflammatory response …