The resurgence of research into cancer metabolism has recently broadened interests
beyond glucose and the Warburg effect to other nutrients, including glutamine. Because …

Glutamine is the most abundant circulating amino acid in blood and muscle and is critical for
many fundamental cell functions in cancer cells, including synthesis of metabolites that …

This first-in-man imaging study evaluated the safety and feasibility of hyperpolarized [1-13C]
pyruvate as an agent for noninvasively characterizing alterations in tumor metabolism for …

Cancer cells must rewire cellular metabolism to satisfy the demands of growth and
proliferation. Although many of the metabolic alterations are largely similar to those in …

Genetic events in cancer activate signalling pathways that alter cell metabolism. Clinical
evidence has linked cell metabolism with cancer outcomes. Together, these observations …

Cancer is a devastating disease that alters the metabolism of a cell and the surrounding
milieu. Metabolomics is a growing and powerful technology capable of detecting hundreds …

1H and 13C NMR spectroscopy is routinely used for the elucidation of structures of newly
synthesized compounds, natural products and semi-synthesized compounds. The …

An extraordinary new technique using hyperpolarized 13C-labeled pyruvate and taking
advantage of increased glycolysis in cancer has the potential to improve the way magnetic …

Metabolic imaging using hyperpolarized magnetic resonance can increase the sensitivity of
MRI, though its ability to inform on relevant changes to biochemistry in humans remains …

Tumors are usually classified into two main categories–benign or malignant, with much
more attention being devoted to the second category given that they are usually associated …