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Synthetic microbial communities (SynComs) of the human gut: design, assembly, and applications
The human gut harbors native microbial communities, forming a highly complex ecosystem.
Synthetic microbial communities (SynComs) of the human gut are an assembly of …
Synthetic microbial communities (SynComs) of the human gut are an assembly of …
[HTML][HTML] Synthetic biology tools to engineer microbial communities for biotechnology
Microbial consortia have been used in biotechnology processes, including fermentation,
waste treatment, and agriculture, for millennia. Today, synthetic biologists are increasingly …
waste treatment, and agriculture, for millennia. Today, synthetic biologists are increasingly …
A metabolic modeling platform for the computation of microbial ecosystems in time and space (COMETS)
Genome-scale stoichiometric modeling of metabolism has become a standard systems
biology tool for modeling cellular physiology and growth. Extensions of this approach are …
biology tool for modeling cellular physiology and growth. Extensions of this approach are …
Systematic assessment of secondary bile acid metabolism in gut microbes reveals distinct metabolic capabilities in inflammatory bowel disease
Background The human gut microbiome performs important functions in human health and
disease. A classic example for host-gut microbial co-metabolism is host biosynthesis of …
disease. A classic example for host-gut microbial co-metabolism is host biosynthesis of …
Engineering microbial consortia for controllable outputs
Much research has been invested into engineering microorganisms to perform desired
biotransformations; nonetheless, these efforts frequently fall short of expected results due to …
biotransformations; nonetheless, these efforts frequently fall short of expected results due to …
Synthetic ecology of microbes: mathematical models and applications
As the indispensable role of natural microbial communities in many aspects of life on Earth
is uncovered, the bottom-up engineering of synthetic microbial consortia with novel functions …
is uncovered, the bottom-up engineering of synthetic microbial consortia with novel functions …
[HTML][HTML] Optimization and scale-up of fermentation processes driven by models
In the era of sustainable development, the use of cell factories to produce various
compounds by fermentation has attracted extensive attention; however, industrial …
compounds by fermentation has attracted extensive attention; however, industrial …
[HTML][HTML] Metabolic modelling approaches for describing and engineering microbial communities
Microbes do not live in isolation but in microbial communities. The relevance of microbial
communities is increasing due to growing awareness of their influence on a huge number of …
communities is increasing due to growing awareness of their influence on a huge number of …
[HTML][HTML] Metabolic engineering of human gut microbiome: recent developments and future perspectives
Many studies have demonstrated that the gut microbiota is associated with human health
and disease. Manipulation of the gut microbiota, eg supplementation of probiotics, has been …
and disease. Manipulation of the gut microbiota, eg supplementation of probiotics, has been …
Bottom-up synthetic ecology study of microbial consortia to enhance lignocellulose bioconversion
Lignocellulose is the most abundant organic carbon polymer on the earth. Its decomposition
and conversion greatly impact the global carbon cycle. Furthermore, it provides feedstock for …
and conversion greatly impact the global carbon cycle. Furthermore, it provides feedstock for …