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Chagas disease: an overview of clinical and epidemiological aspects
Chagas disease, caused by the parasite Trypanosoma cruzi, is a serious health problem in
Latin America and is an emerging disease in non-endemic countries. In recent decades, the …
Latin America and is an emerging disease in non-endemic countries. In recent decades, the …
Chemokines and heart disease: a network connecting cardiovascular biology to immune and autonomic nervous systems
Among the chemokines discovered to date, nineteen are presently considered to be relevant
in heart disease and are involved in all stages of cardiovascular response to injury …
in heart disease and are involved in all stages of cardiovascular response to injury …
Disease Tolerance and Pathogen Resistance Genes May Underlie Trypanosoma cruzi Persistence and Differential Progression to Chagas Disease Cardiomyopathy
Chagas disease is caused by infection with the protozoan Trypanosoma cruzi and affects
over 8 million people worldwide. In spite of a powerful innate and adaptive immune …
over 8 million people worldwide. In spite of a powerful innate and adaptive immune …
Myocardial Chemokine Expression and Intensity of Myocarditis in Chagas Cardiomyopathy Are Controlled by Polymorphisms in CXCL9 and CXCL10
LG Nogueira, RHB Santos, BM Ianni… - PLoS Neglected …, 2012 - journals.plos.org
Background Chronic Chagas cardiomyopathy (CCC), a life-threatening inflammatory dilated
cardiomyopathy, affects 30% of the approximately 8 million patients infected by …
cardiomyopathy, affects 30% of the approximately 8 million patients infected by …
Cytokine networks as targets for preventing and controlling Chagas heart disease
Chagas disease, a neglected disease caused by the protozoan Trypanosoma cruzi, is
endemic in 21 Latin American countries, affecting 6–8 million people. Increasing numbers of …
endemic in 21 Latin American countries, affecting 6–8 million people. Increasing numbers of …
Congenital Transmission of Trypanosoma cruzi: A Review About the Interactions Between the Parasite, the Placenta, the Maternal and the Fetal/Neonatal Immune …
Chagas disease (CD), caused by the protozoan parasite Trypanosoma cruzi, is considered
a neglected tropical disease by the World Health Organization. Congenital transmission of …
a neglected tropical disease by the World Health Organization. Congenital transmission of …
CCR5-Δ32 biology, gene editing, and warnings for the future of CRISPR-Cas9 as a human and humane gene editing tool
MM Xu - Cell & bioscience, 2020 - Springer
Background Biomedical technologies have not just improved human health but also
assisted in the creation of human life. Since the first birth of a healthy baby by in vitro …
assisted in the creation of human life. Since the first birth of a healthy baby by in vitro …
CCR5 and CCR5Δ32 in bacterial and parasitic infections: Thinking chemokine receptors outside the HIV box
The CCR5 molecule was reported in 1996 as the main HIV‐1 co‐receptor. In that same year,
the CCR5Δ32 genetic variant was described as a strong protective factor against HIV‐1 …
the CCR5Δ32 genetic variant was described as a strong protective factor against HIV‐1 …
Genetic susceptibility to Chagas disease: an overview about the infection and about the association between disease and the immune response genes
Chagas disease, which is caused by the flagellate parasite Trypanosoma cruzi, affects 8–10
million people in Latin America. The disease is endemic and is characterised by acute and …
million people in Latin America. The disease is endemic and is characterised by acute and …
Trypanosoma cruzi strains cause different myocarditis patterns in infected mice
Aims Chagas disease pathology is dependent on the infecting Trypanosoma cruzi strain.
However, the relationship between the extent and type of myocarditis caused by different T …
However, the relationship between the extent and type of myocarditis caused by different T …