[HTML][HTML] Cardiovascular disease in diabetes, beyond glucose
RH Eckel, KE Bornfeldt, IJ Goldberg - Cell metabolism, 2021 - cell.com
Despite the decades-old knowledge that diabetes mellitus is a major risk factor for
cardiovascular disease, the reasons for this association are only partially understood. While …
cardiovascular disease, the reasons for this association are only partially understood. While …
Functions of S100 proteins
The S100 protein family consists of 24 members functionally distributed into three main
subgroups: those that only exert intracellular regulatory effects, those with intracellular and …
subgroups: those that only exert intracellular regulatory effects, those with intracellular and …
Chronic e-cigarette use impairs endothelial function on the physiological and cellular levels
Background: The harmful vascular effects of smoking are well established, but the effects of
chronic use of electronic cigarettes (e-cigarettes) on endothelial function are less …
chronic use of electronic cigarettes (e-cigarettes) on endothelial function are less …
Vascular calcification: from pathophysiology to biomarkers
The link between vascular calcification (VC) and increased mortality is now well established.
Over time, as clinical importance of this phenomenon has begun to be fully considered …
Over time, as clinical importance of this phenomenon has begun to be fully considered …
S100A8 and S100A9: DAMPs at the crossroads between innate immunity, traditional risk factors, and cardiovascular disease
Amplification of innate immune responses by endogenous danger‐associated molecular
patterns (DAMPs) promotes inflammation. The involvement of S100A8 and S100A9, DAMPs …
patterns (DAMPs) promotes inflammation. The involvement of S100A8 and S100A9, DAMPs …
S100A8 and S100A9 Induce Cytokine Expression and Regulate the NLRP3 Inflammasome via ROS-Dependent Activation of NF-κB1
JC Simard, A Cesaro, J Chapeton-Montes, M Tardif… - PloS one, 2013 - journals.plos.org
S100A8 and S100A9 are cytoplasmic proteins expressed by phagocytes. High
concentrations of these proteins have been correlated with various inflammatory conditions …
concentrations of these proteins have been correlated with various inflammatory conditions …
Single-cell RNA sequencing uncovers the nuclear decoy lincRNA PIRAT as a regulator of systemic monocyte immunity during COVID-19
M Aznaourova, N Schmerer, H Janga, Z Zhang… - Proceedings of the …, 2022 - pnas.org
The systemic immune response to viral infection is shaped by master transcription factors,
such as NF-κB, STAT1, or PU. 1. Although long noncoding RNAs (lncRNAs) have been …
such as NF-κB, STAT1, or PU. 1. Although long noncoding RNAs (lncRNAs) have been …
Tissue matrix arrays for high-throughput screening and systems analysis of cell function
Cell and protein arrays have demonstrated remarkable utility in the high-throughput
evaluation of biological responses; however, they lack the complexity of native tissue and …
evaluation of biological responses; however, they lack the complexity of native tissue and …
Semaglutide ameliorates obesity-induced cardiac inflammation and oxidative stress mediated via reduction of neutrophil Cxcl2, S100a8, and S100a9 expression
X Pan, L Yang, S Wang, Y Liu, L Yue… - Molecular and Cellular …, 2024 - Springer
Obesity, which is driven by inflammation and oxidative stress, is a risk factor for
cardiovascular disease. Semaglutide, a glucagon-like peptide-1 receptor agonist, is an …
cardiovascular disease. Semaglutide, a glucagon-like peptide-1 receptor agonist, is an …
Meta-analysis derived atopic dermatitis (MADAD) transcriptome defines a robust AD signature highlighting the involvement of atherosclerosis and lipid metabolism …
Background Atopic dermatitis (AD) is a common inflammatory skin disease with limited
treatment options. Several microarray experiments have been conducted on lesional/LS and …
treatment options. Several microarray experiments have been conducted on lesional/LS and …