Objectives During the last decades, several changes of paradigm have modified our view on
how biomaterials' surface characteristics influence the bioresponse. After becoming aware …

Bone tissue has a remarkable ability to regenerate and heal itself. However, large bone
defects and complex fractures still present a significant challenge to the medical community …

Stem cells respond to nanoscale surface features, with changes in cell growth and
differentiation mediated by alterations in cell adhesion. The interaction of nanotopographical …

Orthopedic implants are increasing in global prevalence, with hundreds of thousands of
operations performed annually. However, a significant proportion of these operations …

A key tenet of bone tissue engineering is the development of scaffold materials that can
stimulate stem cell differentiation in the absence of chemical treatment to become …

Current research on surface modifications has yielded advanced implant biomaterials.
Various implant surface modifications have been shown to be promising in improving bone …

Biocompatible surfaces hold key to a variety of biomedical problems that are directly related
to the competition between host-tissue cell integration and bacterial colonisation. A saving …

Biomaterials interact with the biological environment at their surface, making accurate
biophysical characterization of the surface crucially important for understanding subsequent …

This review concerns the importance of length and time on physicochemical interactions
between living tissue and biomaterials that occur on implantation. The review provides …

The biological fixation between the dental implant surfaces and jaw bones should be
considered a prerequisite for the long-term success of implant-supported prostheses. In this …