During aging the immune system (IS) undergoes remarkable changes that collectively are
known as immunosenescence. It is a multifactorial and dynamic phenomenon that affects …

The inflammaging concept was introduced in 2000 by Prof. Franceschi. This was an
evolutionary or rather a revolutionary conceptualization of the immune changes in response …

In this review, we discuss the pathophysiologic and management aspects of acute
sarcopenia in relation to SARS-CoV-2 infection. COVID-19 is as a multi-organ infectious …

Aging is a gradual, continuous series of natural changes in biological, physiological,
immunological, environmental, psychological, behavioral, and social processes. Aging …

Whether and how certain transposable elements with viral origins, such as endogenous
retroviruses (ERVs) dormant in our genomes, can become awakened and contribute to the …

The first paper on “inflammaging” published in 2001 paved the way for a unifying theory on
how and why aging turns out to be the main risk factor for the development of the most …

Ageing is associated with modified function of both innate and adaptive immunity. It is
believed that changes occurring in ageing immune system are responsible for increased …

The initial instance of a severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
infection was observed in December 2019 in the city of Wuhan, China. Subsequently, the …

The JN. 1 variant of COVID‐19 has emerged as the dominant strain worldwide since the end
of 2023. As a subclade of the BA. 2.86 variant, JN. 1 harbors a unique combination of …

Vaccine responsiveness is often reduced in older adults. Yet, our lack of understanding of
low vaccine responsiveness hampers the development of effective vaccination strategies to …