How colonization by microbiota in early life shapes the immune system

T Gensollen, SS Iyer, DL Kasper, RS Blumberg - Science, 2016 - science.org
Microbial colonization of mucosal tissues during infancy plays an instrumental role in the
development and education of the host mammalian immune system. These early-life events …

[HTML][HTML] Gut microbiota in health and disease

I Sekirov, SL Russell, LCM Antunes… - Physiological …, 2010 - journals.physiology.org
Gut microbiota is an assortment of microorganisms inhabiting the length and width of the
mammalian gastrointestinal tract. The composition of this microbial community is host …

[HTML][HTML] The human microbiota in health and disease

B Wang, M Yao, L Lv, Z Ling, L Li - Engineering, 2017 - Elsevier
Trillions of microbes have evolved with and continue to live on and within human beings. A
variety of environmental factors can affect intestinal microbial imbalance, which has a close …

Inflammation and colon cancer

J Terzić, S Grivennikov, E Karin, M Karin - Gastroenterology, 2010 - Elsevier
The connection between inflammation and tumorigenesis is well-established and in the last
decade has received a great deal of supporting evidence from genetic, pharmacological …

Intratumoral microbiota: roles in cancer initiation, development and therapeutic efficacy

L Yang, A Li, Y Wang, Y Zhang - Signal transduction and targeted …, 2023 - nature.com
Microorganisms, including bacteria, viruses, fungi, and other eukaryotes, play critical roles in
human health. An altered microbiome can be associated with complex diseases …

[HTML][HTML] Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells

HJ Wu, II Ivanov, J Darce, K Hattori, T Shima… - Immunity, 2010 - cell.com
Commensal microbes can have a substantial impact on autoimmune disorders, but the
underlying molecular and cellular mechanisms remain largely unexplored. We report that …

Exploring the human microbiome: the potential future role of next-generation sequencing in disease diagnosis and treatment

MA Malla, A Dubey, A Kumar, S Yadav… - Frontiers in …, 2019 - frontiersin.org
The interaction between the human microbiome and immune system has an effect on
several human metabolic functions and impacts our well-being. Additionally, the interaction …

Human gut microbiota and gastrointestinal cancer

C Meng, C Bai, TD Brown, LE Hood… - Genomics, Proteomics …, 2018 - academic.oup.com
Human gut microbiota play an essential role in both healthy and diseased states of humans.
In the past decade, the interactions between microorganisms and tumors have attracted …

[HTML][HTML] Homeostasis and inflammation in the intestine

WS Garrett, JI Gordon, LH Glimcher - Cell, 2010 - cell.com
The gut is home to our largest collection of microbes. The ability of the immune system to
coevolve with the microbiota during postnatal life allows the host and microbiota to coexist in …

[HTML][HTML] Overview of cytokines and nitric oxide involvement in immuno-pathogenesis of inflammatory bowel diseases

I Soufli, R Toumi, H Rafa… - World journal of …, 2016 - ncbi.nlm.nih.gov
Inflammatory bowel diseases (IBDs), including Crohn's disease and ulcerative colitis are
complex disorders with undetermined etiology. Several hypotheses suggest that IBDs result …