Cell–extracellular matrix mechanotransduction in 3D

A Saraswathibhatla, D Indana… - Nature Reviews Molecular …, 2023 - nature.com
Mechanical properties of extracellular matrices (ECMs) regulate essential cell behaviours,
including differentiation, migration and proliferation, through mechanotransduction. Studies …

[HTML][HTML] Cell–scaffold interactions in tissue engineering for oral and craniofacial reconstruction

F Wang, X Cai, Y Shen, L Meng - Bioactive Materials, 2023 - Elsevier
Tissue engineering (TE) is critical in oral and craniofacial reconstruction. One of the most
popular topics on the biomaterial-based tissue regeneration process may be the interaction …

Biomaterials and tissue engineering approaches using glycosaminoglycans for tissue repair: Lessons learned from the native extracellular matrix

R Menezes, R Vincent, L Osorno, P Hu, TL Arinzeh - Acta biomaterialia, 2023 - Elsevier
Glycosaminoglycans (GAGs) are an important component of the extracellular matrix as they
influence cell behavior and have been sought for tissue regeneration, biomaterials, and …

Lift-out cryo-FIBSEM and cryo-ET reveal the ultrastructural landscape of extracellular matrix

B Zens, F Fäßler, JM Hansen, R Hauschild… - Journal of Cell …, 2024 - rupress.org
The extracellular matrix (ECM) serves as a scaffold for cells and plays an essential role in
regulating numerous cellular processes, including cell migration and proliferation. Due to …

Programmable and contractile materials through cell encapsulation in fibrous hydrogel assemblies

MD Davidson, ME Prendergast, E Ban, KL Xu… - Science …, 2021 - science.org
The natural extracellular matrix (ECM) within tissues is physically contracted and remodeled
by cells, allowing the collective sha** of functional tissue architectures. Synthetic materials …

Collagen assembly at the cell surface: dogmas revisited

M Musiime, J Chang, U Hansen, KE Kadler, C Zeltz… - Cells, 2021 - mdpi.com
With the increased awareness about the importance of the composition, organization, and
stiffness of the extracellular matrix (ECM) for tissue homeostasis, there is a renewed need to …

Glycosaminoglycans modulate long-range mechanical communication between cells in collagen networks

X Chen, D Chen, E Ban, KC Toussaint… - Proceedings of the …, 2022 - pnas.org
Cells can sense and respond to mechanical forces in fibrous extracellular matrices (ECMs)
over distances much greater than their size. This phenomenon, termed long-range force …

[HTML][HTML] Multifunctional scaffolds and synergistic strategies in tissue engineering and regenerative medicine

N Muzzio, S Moya, G Romero - Pharmaceutics, 2021 - mdpi.com
The increasing demand for organ replacements in a growing world with an aging population
as well as the loss of tissues and organs due to congenital defects, trauma and diseases has …

[HTML][HTML] Hierarchical ultrastructure: An overview of what is known about tendons and future perspective for tendon engineering

S Zhang, W Ju, X Chen, Y Zhao, L Feng, Z Yin… - Bioactive materials, 2022 - Elsevier
Abnormal tendons are rarely ever repaired to the natural structure and morphology of
normal tendons. To better guide the repair and regeneration of injured tendons through a …

[HTML][HTML] The role of glycans in the mechanobiology of cancer

A Purushothaman, M Mohajeri, TP Lele - Journal of Biological Chemistry, 2023 - Elsevier
Although cancer is a genetic disease, physical changes such as stiffening of the
extracellular matrix also commonly occur in cancer. Cancer cells sense and respond to …