Bioorthogonal chemistry and its applications
RE Bird, SA Lemmel, X Yu, QA Zhou - Bioconjugate Chemistry, 2021 - ACS Publications
Bioorthogonal chemistry is a set of methods using the chemistry of non-native functional
groups to explore and understand biology in living organisms. In this review, we summarize …
groups to explore and understand biology in living organisms. In this review, we summarize …
Bioorthogonal chemistry
Bioorthogonal chemistry represents a class of high-yielding chemical reactions that proceed
rapidly and selectively in biological environments without side reactions towards …
rapidly and selectively in biological environments without side reactions towards …
Click chemistry strategies for the accelerated synthesis of functional macromolecules
Z Geng, JJ Shin, Y ** bioorthogonal probes to span a spectrum of reactivities
SS Nguyen, JA Prescher - Nature Reviews Chemistry, 2020 - nature.com
Bioorthogonal chemistries enable researchers to interrogate biomolecules in living systems.
These reactions are highly selective and biocompatible, and can be performed in many …
These reactions are highly selective and biocompatible, and can be performed in many …
Recent advances in activity-based probes (ABPs) and affinity-based probes (A f BPs) for profiling of enzymes
Activity-based protein profiling (ABPP) is a technique that uses highly selective active-site
targeted chemical probes to label and monitor the state of proteins. ABPP integrates the …
targeted chemical probes to label and monitor the state of proteins. ABPP integrates the …
Click chemistry for drug development and diverse chemical–biology applications
Chemistry, traditionally being the science of synthesis and structural manipulations of
molecules, has gradually undertaken the more challenging task of biology-oriented …
molecules, has gradually undertaken the more challenging task of biology-oriented …