Genes specifying long non-coding RNAs (lncRNAs) occupy a large fraction of the genomes
of complex organisms. The term 'lncRNAs' encompasses RNA polymerase I (Pol I), Pol II …

Long non-coding RNAs (lncRNAs) are diverse transcription products emanating from
thousands of loci in mammalian genomes. Cis-acting lncRNAs, which constitute a …

Abstract ChIP-Atlas (https://chip-atlas. org) is a web service providing both GUI-and API-
based data-mining tools to reveal the architecture of the transcription regulatory landscape …

We have known for decades that long noncoding RNAs (lncRNAs) can play essential
functions across most forms of life. The maintenance of chromosome length requires an …

Genome-wide sequencing has led to the discovery of thousands of long non-coding RNA
(lncRNA) loci in the human genome, but evidence of functional significance has remained …

Abstract Topologically Associating Domains (TADs) have been suggested to facilitate and
constrain enhancer–promoter interactions. However, the role of TAD boundaries in …

The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Abstract Background Several long noncoding RNAs (lncRNAs) have been shown to function
as components of molecular machines that play fundamental roles in biology. While the …

RNA has been classically known to play central roles in biology, including maintaining
telomeres, protein synthesis, and in sex chromosome compensation. While thousands of …

Background Gene expression differences between species are driven by both cis and trans
effects. Whereas cis effects are caused by genetic variants located on the same DNA …