Ferroptosis: mechanisms and links with diseases
Ferroptosis is an iron-dependent cell death, which is different from apoptosis, necrosis,
autophagy, and other forms of cell death. The process of ferroptotic cell death is defined by …
autophagy, and other forms of cell death. The process of ferroptotic cell death is defined by …
Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions
C Qin, S Yang, YH Chu, H Zhang, XW Pang… - Signal transduction and …, 2022 - nature.com
Ischemic stroke is caused primarily by an interruption in cerebral blood flow, which induces
severe neural injuries, and is one of the leading causes of death and disability worldwide …
severe neural injuries, and is one of the leading causes of death and disability worldwide …
[HTML][HTML] Ferroptosis as a novel therapeutic target for cardiovascular disease
X Wu, Y Li, S Zhang, X Zhou - Theranostics, 2021 - ncbi.nlm.nih.gov
Cell death is an important component of the pathophysiology of cardiovascular disease. An
understanding of how cardiomyocytes die, and why regeneration of cells in the heart is …
understanding of how cardiomyocytes die, and why regeneration of cells in the heart is …
[HTML][HTML] Molecular mechanisms of ferroptosis and their involvement in brain diseases
I Costa, DJ Barbosa, S Benfeito, V Silva… - Pharmacology & …, 2023 - Elsevier
Ferroptosis is a type of regulated cell death characterized by intracellular accumulation of
iron and reactive oxygen species, inhibition of system Xc-, glutathione depletion …
iron and reactive oxygen species, inhibition of system Xc-, glutathione depletion …
Ferrostatin-1 alleviates lipopolysaccharide-induced acute lung injury via inhibiting ferroptosis
P Liu, Y Feng, H Li, X Chen, G Wang, S Xu, Y Li… - Cellular & molecular …, 2020 - Springer
Background Ferroptosis is a newly recognized type of cell death, which is different from
traditional necrosis, apoptosis or autophagic cell death. However, the position of ferroptosis …
traditional necrosis, apoptosis or autophagic cell death. However, the position of ferroptosis …
Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death
Ferroptotic death is the penalty for losing control over three processes—iron metabolism,
lipid peroxidation and thiol regulation—that are common in the pro-inflammatory …
lipid peroxidation and thiol regulation—that are common in the pro-inflammatory …
Iron homeostasis and ferroptosis in human diseases: mechanisms and therapeutic prospects
Iron, an essential mineral in the body, is involved in numerous physiological processes,
making the maintenance of iron homeostasis crucial for overall health. Both iron overload …
making the maintenance of iron homeostasis crucial for overall health. Both iron overload …
Mesenchymal stem cells protect against ferroptosis via exosome-mediated stabilization of SLC7A11 in acute liver injury
F Lin, W Chen, J Zhou, J Zhu, Q Yao, B Feng… - Cell death & …, 2022 - nature.com
Mesenchymal stem cells (MSCs) have attracted interest for their potential to alleviate liver
injury. Here, the protective effect of MSCs on carbon tetrachloride (CCl4)-induced acute liver …
injury. Here, the protective effect of MSCs on carbon tetrachloride (CCl4)-induced acute liver …
The application of ferroptosis in diseases
Ferroptosis is a new kind of regulated cell death that is characterized by highly iron-
dependent lipid peroxidation. Ferroptosis involves various biology processes, such as iron …
dependent lipid peroxidation. Ferroptosis involves various biology processes, such as iron …
Nuclear receptor coactivator 4-mediated ferritinophagy contributes to cerebral ischemia-induced ferroptosis in ischemic stroke
C Li, G Sun, B Chen, L Xu, Y Ye, J He, Z Bao… - Pharmacological …, 2021 - Elsevier
Ischemic stroke poses a significant health risk due to its high rate of disability and mortality.
To address this problem, several therapeutic approaches have been proposed, including …
To address this problem, several therapeutic approaches have been proposed, including …