The fragmentation pathways of protonated peptides are reviewed in the present paper
paying special attention to classification of the known fragmentation channels into a simple …

Protein identification and peptide sequencing by tandem mass spectrometry requires
knowledge of how peptides fragment in the gas phase, specifically which bonds are broken …

The most commonly used activation method in the tandem mass spectrometry (MS) of
peptides and proteins is energetic collisions with a neutral target gas. The overall process of …

A database of 5500 unique peptide tandem mass spectra acquired in an ion trap mass
spectrometer was assembled for peptides derived from proteins digested with trypsin …

Collision-induced dissociation (CID) is a common ion activation technique used to energize
mass-selected peptide ions during tandem mass spectrometry. Characteristic fragment ions …

Abstract I. Introduction 87 II. Discussion 88 A. The Backbone Cleavages of (M‐H)− Parent
Anions of Peptides 88 1. α‐and β‐Backbone Cleavages 89 2. The β′ Cleavage 92 3. The …

Electrospray ionization provides a “treasure trove” of metal containing ions whose
fundamental reactivity can be studied via collision induced dissociation and ion–molecule …

One of the major factors governing the “top-down” sequence analysis of intact multiply
protonated proteins by tandem mass spectrometry is the effect of the precursor ion charge …

The dissociation of the amide (peptide) bond in protonated peptides,[M+ H]+, is discussed in
terms of the structures and energetics of the resulting N‐terminal bn and C‐terminal yn …

Unimolecular fragmentation reactions of peptides in low‐energy collision‐induced
dissociation are reviewed in the mechanistic context of five‐membered ring formation. This …