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[HTML][HTML] Cyclodextrin inclusion complexes for improved drug bioavailability and activity: synthetic and analytical aspects
Many active pharmaceutical ingredients show low oral bioavailability due to factors such as
poor solubility and physical and chemical instability. The formation of inclusion complexes …
poor solubility and physical and chemical instability. The formation of inclusion complexes …
Options for topical treatment of oxidative eye diseases with a special focus on retinopathies
C Russo, D Rusciano, R Santangelo, L Malaguarnera - Medicina, 2024 - mdpi.com
Antioxidants, usually administered orally through the systemic route, are known to
counteract the harmful effects of oxidative stress on retinal cells. The formulation of these …
counteract the harmful effects of oxidative stress on retinal cells. The formulation of these …
Novel papaverine metal complexes with potential anticancer activities
Cancer is one of the leading causes of death worldwide. Although several potential
therapeutic agents have been developed to efficiently treat cancer, some side effects can …
therapeutic agents have been developed to efficiently treat cancer, some side effects can …
Zein-vs PLGA-based nanoparticles containing rutin: A comparative investigation
In the last few decades, several natural and synthetic polymers have been used as starting
material for the development of innovative polymeric nanoparticles able to encapsulate …
material for the development of innovative polymeric nanoparticles able to encapsulate …
Targeted co-delivery of doxorubicin and methotrexate to breast cancer cells by a pH-sensitive biocompatible polymeric system based on β-cyclodextrin crosslinked …
S Karimi, H Namazi - European Polymer Journal, 2022 - Elsevier
Nowadays, co-delivery of multiple therapeutics and combinational therapies using a delivery
system is a promising approach to attain a synergistic anticancer effect. Hence, in the …
system is a promising approach to attain a synergistic anticancer effect. Hence, in the …
[HTML][HTML] Bicalutamide anticancer activity enhancement by formulation of soluble inclusion complexes with cyclodextrins
Bicalutamide (BCL) is a nonsteroidal antiandrogen drug that represents an alternative to
castration in the treatment of prostate cancer, due to its relatively long half-life and tolerable …
castration in the treatment of prostate cancer, due to its relatively long half-life and tolerable …
[HTML][HTML] Development of chitosan/cyclodextrin nanospheres for levofloxacin ocular delivery
F De Gaetano, A Marino, A Marchetta, C Bongiorno… - Pharmaceutics, 2021 - mdpi.com
Levofloxacin (LVF) is an antibacterial drug approved for the treatment of ocular infections.
However, due to the low ocular bioavailability, high doses are needed, causing bacterial …
However, due to the low ocular bioavailability, high doses are needed, causing bacterial …
Synthesis of β-cyclodextrin grafted rhombohedral-CuO antioxidant nanozyme for detection of dopamine and hexavalent chromium through off–on strategy of …
For the last few decades, peroxidase mimicking inorganic nanoparticles are widely used as
compared to natural peroxidase due to some basic advantages especially high durability …
compared to natural peroxidase due to some basic advantages especially high durability …
Label-free detection of epinephrine using flower-like biomimetic CuS antioxidant nanozymes
A biosensor comprising crystalline CuS nanoparticles (NPs) was synthesized via a one-step
simple coprecipitation route without involvement of a surfactant. The powder X-ray diffraction …
simple coprecipitation route without involvement of a surfactant. The powder X-ray diffraction …
Enhanced physicochemical properties and herbicidal activity of an environment-friendly clathrate formed by β-cyclodextrin and herbicide cyanazine
S Gao, J Jiang, X Li, Y Liu, L Zhao, Y Fu, F Ye - Journal of Molecular Liquids, 2020 - Elsevier
Cyanazine is usually dissolved in organic reagents during use due to the poor solubility in
water. However, cyanazine residues in the environment may cause serious harm to the soil …
water. However, cyanazine residues in the environment may cause serious harm to the soil …