[HTML][HTML] Cyclodextrin inclusion complexes for improved drug bioavailability and activity: synthetic and analytical aspects

Á Sarabia-Vallejo, MM Caja, AI Olives, MA Martín… - Pharmaceutics, 2023 - mdpi.com
Many active pharmaceutical ingredients show low oral bioavailability due to factors such as
poor solubility and physical and chemical instability. The formation of inclusion complexes …

Options for topical treatment of oxidative eye diseases with a special focus on retinopathies

C Russo, D Rusciano, R Santangelo, L Malaguarnera - Medicina, 2024 - mdpi.com
Antioxidants, usually administered orally through the systemic route, are known to
counteract the harmful effects of oxidative stress on retinal cells. The formulation of these …

Novel papaverine metal complexes with potential anticancer activities

A Gaber, WF Alsanie, DN Kumar, MS Refat, EM Saied - Molecules, 2020 - mdpi.com
Cancer is one of the leading causes of death worldwide. Although several potential
therapeutic agents have been developed to efficiently treat cancer, some side effects can …

Zein-vs PLGA-based nanoparticles containing rutin: A comparative investigation

A Gagliardi, D Paolino, N Costa, M Fresta… - Materials Science and …, 2021 - Elsevier
In the last few decades, several natural and synthetic polymers have been used as starting
material for the development of innovative polymeric nanoparticles able to encapsulate …

Targeted co-delivery of doxorubicin and methotrexate to breast cancer cells by a pH-sensitive biocompatible polymeric system based on β-cyclodextrin crosslinked …

S Karimi, H Namazi - European Polymer Journal, 2022 - Elsevier
Nowadays, co-delivery of multiple therapeutics and combinational therapies using a delivery
system is a promising approach to attain a synergistic anticancer effect. Hence, in the …

[HTML][HTML] Bicalutamide anticancer activity enhancement by formulation of soluble inclusion complexes with cyclodextrins

F De Gaetano, MC Cristiano, D Paolino, C Celesti… - Biomolecules, 2022 - mdpi.com
Bicalutamide (BCL) is a nonsteroidal antiandrogen drug that represents an alternative to
castration in the treatment of prostate cancer, due to its relatively long half-life and tolerable …

[HTML][HTML] Development of chitosan/cyclodextrin nanospheres for levofloxacin ocular delivery

F De Gaetano, A Marino, A Marchetta, C Bongiorno… - Pharmaceutics, 2021 - mdpi.com
Levofloxacin (LVF) is an antibacterial drug approved for the treatment of ocular infections.
However, due to the low ocular bioavailability, high doses are needed, causing bacterial …

Synthesis of β-cyclodextrin grafted rhombohedral-CuO antioxidant nanozyme for detection of dopamine and hexavalent chromium through off–on strategy of …

S Ali, S Sikdar, S Basak, D Das, D Roy, MS Haydar… - Microchemical …, 2022 - Elsevier
For the last few decades, peroxidase mimicking inorganic nanoparticles are widely used as
compared to natural peroxidase due to some basic advantages especially high durability …

Label-free detection of epinephrine using flower-like biomimetic CuS antioxidant nanozymes

S Ali, S Sikdar, S Basak, MS Haydar, K Mallick… - Inorganic …, 2023 - ACS Publications
A biosensor comprising crystalline CuS nanoparticles (NPs) was synthesized via a one-step
simple coprecipitation route without involvement of a surfactant. The powder X-ray diffraction …

Enhanced physicochemical properties and herbicidal activity of an environment-friendly clathrate formed by β-cyclodextrin and herbicide cyanazine

S Gao, J Jiang, X Li, Y Liu, L Zhao, Y Fu, F Ye - Journal of Molecular Liquids, 2020 - Elsevier
Cyanazine is usually dissolved in organic reagents during use due to the poor solubility in
water. However, cyanazine residues in the environment may cause serious harm to the soil …