Rheumatoid arthritis (RA) is an autoimmune disease, resulting in a chronic, systemic
inflammatory disorder. It may affect many tissues and organs, but it primarily affects the …

Asthma is the most common chronic childhood disease in developed nations and is a
complex disease that has high social and economic costs. Asthma and its associated …

The Saccharomyces cerevisiae protein ELO2p is involved in the elongation of saturated and
monounsaturated fatty acids. Among several sequences with limited identity with the S …

Objective Significant variation in interleukin‐1β (IL‐1β) protein secretion between subjects
has been observed when using a lipopolysaccharide (LPS)/ATP–mediated ex vivo blood …

Adenylate/uridylate-rich element (ARE)-mediated mRNA turnover is an important regulatory
component of gene expression for innate and specific immunity, in the hematopoietic …

Objective To undertake a systematic whole‐genome screen to identify regions exhibiting
genetic linkage to rheumatoid arthritis (RA). Methods Two hundred fifty‐two RA‐affected …

The balance between interleukin-1 (IL-1) and its competitive antagonist IL-1 receptor
antagonist (IL-1Ra) may contribute to the pathogenesis of rheumatoid arthritis (RA). We …

OBJECTIVE: To analyze the association of genetic polymorphisms of pro-inflammatory
cytokines with rheumatoid arthritis (RA) in comparison with healthy controls from Northern …

C‐reactive protein (CRP) is an inflammatory marker associated with increased
cardiovascular risk. Production of CRP is regulated by interleukin (IL)‐1β, IL‐1 receptor …

Chemokines are critical for the inflammatory process in autoimmune diseases such as
rheumatoid arthritis (RA). The chemokine receptor-5 (CCR5) mediates chemotaxis by CC …