Alzheimer disease (AD) is characterized by progressive cognitive decline in older
individuals accompanied by the presence of two pathological protein aggregates—amyloid …

Synapse loss and damage are central features of Alzheimer's disease (AD) and contribute to
the onset and progression of its behavioural and physiological features. Here we review the …

Mitochondria play a vital role in the nervous system, as they are responsible for generating
energy in the form of ATP and regulating cellular processes such as calcium (Ca 2+) …

Alzheimer's disease (AD) is the most frequent cause of age-related neurodegeneration and
cognitive impairment, and there are currently no broadly effective therapies. The underlying …

Brain insulin signaling controls peripheral energy metabolism and plays a key role in the
regulation of mood and cognition. Epidemiological studies have indicated a strong …

Alzheimer's disease (AD) is one of the major reasons for 60-80% cases of senile dementia
occurring as a result of the accumulation of plaques and tangles in the hippocampal and …

Alzheimer's disease (AD) remains one of the most formidable neurological disorders,
affecting millions globally. This review provides a holistic overview of the therapeutic …

Alzheimer's disease (AD) is a neurodegenerative disease that manifests its pathology
through synaptic damage, mitochondrial abnormalities, microRNA deregulation, hormonal …

This review is focused on several psychiatric disorders in which cognitive impairment is a
major component of the disease, influencing life quality. There are plenty of data proving that …

Hypoglycemia, a common consequence of diabetes treatment, is associated with severe
morbidity and mortality and has become a major barrier to intensifying antidiabetic therapy …