The nuclear factor-kappaB (NF-κB) signaling pathway is considered as a potential
therapeutic target in cancer therapy. It has been well established that transcription factor NF …

The increasing incidence of obesity and its co-morbid conditions poses a great challenge to
global health. In addition to cardiovascular disease and diabetes, epidemiological data …

Oxidative damage and inflammation have been pointed out in preclinical studies as the root
cause of cancer and other chronic diseases such as diabetes, hypertension, Alzheimer's …

Objective The associations between oral diseases and increased risk of pancreatic cancer
have been reported in several prospective cohort studies. In this study, we measured …

Curcumin (diferuloylmethane), an orange-yellow component of turmeric or curry powder, is a
polyphenol natural product isolated from the rhizome of the plant Curcuma longa. For …

A wide array of phenolic substances, particularly those present in edible and medicinal
plants, have been reported to possess substantial anticarcinogenic and antimutagenic …

Purpose: Pancreatic cancer is almost always lethal, and the only US Food and Drug
Administration–approved therapies for it, gemcitabine and erlotinib, produce objective …

There is a growing interest in herbal medicine. Scientific studies have demonstrated the
beneficial pharmacological effects of curcumin. Curcumin is a bright yellow spice, derived …

Cancer is primarily a disease of old age, and that life style plays a major role in the
development of most cancers is now well recognized. While plant-based formulations have …

Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer death in the
United States with a median survival of< 6 mo and a dismal 5-yr survival rate of 3%–5%. The …