Malaria remains a major cause of morbidity and mortality in the tropics, with Plasmodium
falciparum responsible for the majority of the disease burden and P. vivax being the …

▪ Abstract Mosquitoes of the genus Anopheles transmit malaria parasites to humans.
Anopheles mosquito species vary in their vector potential because of environmental …

Malaria caused by Plasmodium falciparum remains a major public health threat, especially
among children and pregnant women in Africa. An effective malaria vaccine would be a …

Summary Pfs230 domain 1 (Pfs230D1) is an advanced malaria transmission-blocking
vaccine antigen demonstrating high functional activity in clinical trials. However, the …

Malaria remains one of the world's worst health problems with 1.5 to 2.7 million deaths
annually; these deaths are primarily among children under 5 years of age and pregnant …

Malaria is a vector-borne disease of global importance, with the vast majority of its life-
threatening cases caused by infection with Plasmodium falciparum parasites. Repeated …

Plasmodium falciparum gametocyte kinetics and infectivity may differ between chronic and
incident infections. In the current study, we assess parasite kinetics and infectivity to …

Infection with Plasmodium can elicit antibodies that inhibit parasite survival in the mosquito,
when they are ingested in an infectious blood meal. Here, we determine the transmission …

The efficient spread of malaria from infected humans to mosquitoes is a major challenge for
malaria elimination initiatives. Gametocytes are the only Plasmodium life stage infectious to …

Introduction Transmission-blocking vaccines (TBV) prevent community spread of malaria by
targeting mosquito sexual stage parasites, a life-cycle bottleneck, and will be used in …