Curvature in biological systems: its quantification, emergence, and implications across the scales

B Schamberger, R Ziege, K Anselme… - advanced …, 2023 - Wiley Online Library
Surface curvature both emerges from, and influences the behavior of, living objects at length
scales ranging from cell membranes to single cells to tissues and organs. The relevance of …

Biomolecular condensates in contact with membranes

A Mangiarotti, R Dimova - Annual Review of Biophysics, 2024 - annualreviews.org
Biomolecular condensates are highly versatile membraneless organelles involved in a
plethora of cellular processes. Recent years have witnessed growing evidence of the …

Lipid nanoparticle topology regulates endosomal escape and delivery of RNA to the cytoplasm

L Zheng, SR Bandara, Z Tan, W Pezeshkian, M König, TA Wassenaar… - Nature …, 2020 - nature.com
Many biological processes involve large-scale changes in membrane shape. Computer
simulations of these processes are challenging since they occur across a wide range of …

Remodeling of membrane shape and topology by curvature elasticity and membrane tension

R Lipowsky - Advanced Biology, 2022 - Wiley Online Library
Cellular membranes exhibit a fascinating variety of different morphologies, which are
continuously remodeled by transformations of membrane shape and topology. This …

Molecular mechanism of GPCR spatial organization at the plasma membrane

G Kockelkoren, L Lauritsen, CG Shuttle… - Nature Chemical …, 2024 - nature.com
G-protein-coupled receptors (GPCRs) mediate many critical physiological processes. Their
spatial organization in plasma membrane (PM) domains is believed to encode signaling …

Giant vesicles and their use in assays for assessing membrane phase state, curvature, mechanics, and electrical properties

R Dimova - Annual review of biophysics, 2019 - annualreviews.org
Giant unilamellar vesicles represent a promising and extremely useful model biomembrane
system for systematic measurements of mechanical, thermodynamic, electrical, and …

Optimization of the inverted emulsion method for high‐yield production of biomimetic giant unilamellar vesicles

A Moga, N Yandrapalli, R Dimova… - ChemBioChem, 2019 - Wiley Online Library
In the field of bottom‐up synthetic biology, lipid vesicles provide an important role in the
construction of artificial cells. Giant unilamellar vesicles (GUVs), due to their membrane's …