The impact of loading, unloading, ageing and injury on the human tendon

SP Magnusson, M Kjaer - The Journal of physiology, 2019 - Wiley Online Library
A tendon transfers force from the contracting muscle to the skeletal system to produce
movement and is therefore a crucial component of the entire muscle‐tendon complex and its …

Biomaterials and tissue engineering approaches using glycosaminoglycans for tissue repair: Lessons learned from the native extracellular matrix

R Menezes, R Vincent, L Osorno, P Hu, TL Arinzeh - Acta biomaterialia, 2023 - Elsevier
Glycosaminoglycans (GAGs) are an important component of the extracellular matrix as they
influence cell behavior and have been sought for tissue regeneration, biomaterials, and …

Interfibrillar shear stress is the loading mechanism of collagen fibrils in tendon

SE Szczesny, DM Elliott - Acta biomaterialia, 2014 - Elsevier
Despite the critical role tendons play in transmitting loads throughout the musculoskeletal
system, little is known about the microstructural mechanisms underlying their mechanical …

Decorin expression is important for age-related changes in tendon structure and mechanical properties

AA Dunkman, MR Buckley, MJ Mienaltowski… - Matrix Biology, 2013 - Elsevier
The aging population is at an increased risk of tendon injury and tendinopathy. Elucidating
the molecular basis of tendon aging is crucial to understanding the age-related changes in …

Age-and race-related differences in human scleral material properties

R Grytz, MA Fazio, V Libertiaux, L Bruno… - … & visual science, 2014 - iovs.arvojournals.org
Purpose.: We tested the hypothesis that there are age-and race-related differences in
posterior scleral material properties, using eyes from human donors of European (20–90 …

Frequency domain updating of thin-walled workpiece dynamics using reduced order substructuring method in machining

O Tuysuz, Y Altintas - Journal of Manufacturing …, 2017 - asmedigitalcollection.asme.org
The structural dynamics of thin-walled parts vary as the material is removed during
machining. This paper presents a new, computationally efficient reduced order dynamic …

[HTML][HTML] Structure–function relationships of postnatal tendon development: A parallel to healing

BK Connizzo, SM Yannascoli, LJ Soslowsky - Matrix Biology, 2013 - Elsevier
This review highlights recent research on structure–function relationships in tendon and
comments on the parallels between development and healing. The processes of tendon …

Effects of decorin proteoglycan on fibrillogenesis, ultrastructure, and mechanics of type I collagen gels

SP Reese, CJ Underwood, JA Weiss - Matrix Biology, 2013 - Elsevier
The proteoglycan decorin is known to affect both the fibrillogenesis and the resulting
ultrastructure of in vitro polymerized collagen gels. However, little is known about its effects …

Evidence against proteoglycan mediated collagen fibril load transmission and dynamic viscoelasticity in tendon

G Fessel, JG Snedeker - Matrix Biology, 2009 - Elsevier
The glycosaminoglycan (GAG) dermatan sulfate and chondroitin sulfate side-chains of small
leucine-rich proteoglycans have been increasingly posited to act as molecular cross links …

Contribution of glycosaminoglycans to viscoelastic tensile behavior of human ligament

TJ Lujan, CJ Underwood… - Journal of applied …, 2009 - journals.physiology.org
The viscoelastic properties of human ligament potentially guard against structural failure, yet
the microstructural origins of these transient behaviors are unknown. Glycosaminoglycans …