Computational models in cardiology

SA Niederer, J Lumens, NA Trayanova - Nature reviews cardiology, 2019 - nature.com
The treatment of individual patients in cardiology practice increasingly relies on advanced
imaging, genetic screening and devices. As the amount of imaging and other diagnostic …

Precision medicine in human heart modeling: perspectives, challenges, and opportunities

M Peirlinck, FS Costabal, J Yao, JM Guccione… - … and modeling in …, 2021 - Springer
Precision medicine is a new frontier in healthcare that uses scientific methods to customize
medical treatment to the individual genes, anatomy, physiology, and lifestyle of each person …

Physics-informed neural networks for cardiac activation map**

F Sahli Costabal, Y Yang, P Perdikaris… - Frontiers in …, 2020 - frontiersin.org
A critical procedure in diagnosing atrial fibrillation is the creation of electro-anatomic
activation maps. Current methods generate these map**s from interpolation using a few …

MFEM: A modular finite element methods library

R Anderson, J Andrej, A Barker, J Bramwell… - … & Mathematics with …, 2021 - Elsevier
MFEM is an open-source, lightweight, flexible and scalable C++ library for modular finite
element methods that features arbitrary high-order finite element meshes and spaces …

The openCARP simulation environment for cardiac electrophysiology

G Plank, A Loewe, A Neic, C Augustin… - Computer methods and …, 2021 - Elsevier
Abstract Background and Objective: Cardiac electrophysiology is a medical specialty with a
long and rich tradition of computational modeling. Nevertheless, no community standard for …

[HTML][HTML] A comprehensive and biophysically detailed computational model of the whole human heart electromechanics

M Fedele, R Piersanti, F Regazzoni, M Salvador… - Computer Methods in …, 2023 - Elsevier
While ventricular electromechanics is extensively studied in both physiological and
pathological conditions, four-chamber heart models have only been addressed recently; …

[HTML][HTML] A framework for the generation of digital twins of cardiac electrophysiology from clinical 12-leads ECGs

K Gillette, MAF Gsell, AJ Prassl, E Karabelas… - Medical image …, 2021 - Elsevier
Abstract Cardiac digital twins (Cardiac Digital Twin (CDT) s) of human electrophysiology
(Electrophysiology (EP)) are digital replicas of patient hearts derived from clinical data that …

Arrhythmia risk stratification of patients after myocardial infarction using personalized heart models

HJ Arevalo, F Vadakkumpadan, E Guallar… - Nature …, 2016 - nature.com
Sudden cardiac death (SCD) from arrhythmias is a leading cause of mortality. For patients at
high SCD risk, prophylactic insertion of implantable cardioverter defibrillators (ICDs) reduces …

Personalized virtual-heart technology for guiding the ablation of infarct-related ventricular tachycardia

A Prakosa, HJ Arevalo, D Deng, PM Boyle… - Nature biomedical …, 2018 - nature.com
Ventricular tachycardia (VT), which can lead to sudden cardiac death, occurs frequently in
patients with myocardial infarction. Catheter-based radio-frequency ablation of cardiac …

Integrated heart—coupling multiscale and multiphysics models for the simulation of the cardiac function

A Quarteroni, T Lassila, S Rossi… - Computer Methods in …, 2017 - Elsevier
Mathematical modeling of the human heart and its function can expand our understanding of
various cardiac diseases, which remain the most common cause of death in the developed …