Distinct coordination chemistry of Fe (III)-based MRI probes

EA Kras, EM Snyder, GE Sokolow… - Accounts of Chemical …, 2022 - ACS Publications
Conspectus Contrast agents are used in approximately 40% of all magnetic resonance
imaging (MRI) procedures to improve the quality of the images based on the distribution and …

Low-molecular-weight Fe (III) complexes for MRI contrast agents

S Chen, L An, S Yang - Molecules, 2022 - mdpi.com
Fe (III) complexes have again attracted much attention for application as MRI contrast agents
in recent years due to their high thermodynamic stability, low long-term toxicity, and large …

Hyper-CEST NMR of metal organic polyhedral cages reveals hidden diastereomers with diverse guest exchange kinetics

J Jayapaul, S Komulainen, VV Zhivonitko… - Nature …, 2022 - nature.com
Guest capture and release are important properties of self-assembling nanostructures. Over
time, a significant fraction of guests might engage in short-lived states with different …

Phase-Pure Zirconium Metal–Organic Polyhedra Enabled by a Ligand Substitution Strategy

MG Sullivan, HK Welgama, MR Crawley… - Chemistry of …, 2023 - ACS Publications
Zirconium-based metal–organic polyhedra (ZrMOPs) are attractive due to their high
stabilities, low-cost building blocks, and solubilities relative to their metal–organic framework …

Synthesis of 177Lu-Labeled, Somatostatin-2 Receptor-Targeted Metalla-Assemblies: Challenges in the Design of Supramolecular Radiotherapeutics

S Deiser, M Drexler, G Moreno-Alcántar, M Irl… - Inorganic …, 2023 - ACS Publications
Self-assembled supramolecular coordination complexes (SCCs) hold promise for
biomedical applications in cancer therapy, although their potential in the field of nuclear …

Redox-Responsive MRI Probes Based on First-Row Transition-Metal Complexes

JR Morrow, JJ Raymond, MSI Chowdhury… - Inorganic …, 2022 - ACS Publications
The presence of multiple oxidation and spin states of first-row transition-metal complexes
facilitates the development of switchable MRI probes. Redox-responsive probes capitalize …

Selective separation of planar and non-planar hydrocarbons using an aqueous Pd 6 interlocked cage

D Chakraborty, R Saha, JK Clegg, PS Mukherjee - Chemical Science, 2022 - pubs.rsc.org
Polycyclic aromatic hydrocarbons (PAHs) find multiple applications ranging from fabric dyes
to optoelectronic materials. Hydrogenation of PAHs is often employed for their purification or …

An octahedral coordination cage with six Fe (iii) centers as a T 1 MRI probe

A Dissanayake, JA Spernyak, JR Morrow - Chemical Communications, 2024 - pubs.rsc.org
The incorporation of multiple Fe (III) centers bridged by rigid ligands into a coordination cage
represents a powerful approach for designing effective MRI contrast agents. In this context …

Assembling a new generation of radiopharmaceuticals with supramolecular theranostics

G Moreno-Alcántar, M Drexler, A Casini - Nature Reviews Chemistry, 2024 - nature.com
Supramolecular chemistry has been used to tackle some of the major challenges in modern
science, including cancer therapy and diagnosis. Supramolecular platforms provide …

Fe(III) T1 MRI Probes Containing Phenolate or Hydroxypyridine-Appended Triamine Chelates and a Coordination Site for Bound Water

R Cineus, SM Abozeid, GE Sokolow… - Inorganic …, 2023 - ACS Publications
Fe (III) complexes containing a triamine framework and phenolate or hydroxypyridine donors
are characterized and studied as T 1 MRI probes. In contrast to most Fe (III) MRI probes of …