Computational translation framework identifies biochemical reaction networks with special topologies and their long-term dynamics

H Hong, BS Hernandez, J Kim, JK Kim - SIAM Journal on Applied …, 2023‏ - SIAM
Long-term behaviors of biochemical systems are described by steady states in deterministic
models and stationary distributions in stochastic models. Obtaining their analytic solutions …

Stochastic chemical reaction networks for robustly approximating arbitrary probability distributions

D Cappelletti, A Ortiz-Muñoz, DF Anderson… - Theoretical Computer …, 2020‏ - Elsevier
We show that discrete distributions on the d-dimensional non-negative integer lattice can be
approximated arbitrarily well via the marginals of stationary distributions for various classes …

Boundary-induced slow mixing for Markov chains and its application to stochastic reaction networks

WTL Fan, J Kim, C Yuan - arxiv preprint arxiv:2407.12166, 2024‏ - arxiv.org
Markov chains on the non-negative quadrant of dimension $ d $ are often used to model the
stochastic dynamics of the number of $ d $ entities, such as $ d $ chemical species in …

A Scaling Approach to Stochastic Chemical Reaction Networks

L Laurence, P Robert - arxiv preprint arxiv:2310.01949, 2023‏ - arxiv.org
We investigate the asymptotic properties of Markov processes associated to stochastic
chemical reaction networks (CRNs) driven by the kinetics of the law of mass action. Their …

Mixing times for two classes of stochastically modeled reaction networks

DF Anderson, J Kim - arxiv preprint arxiv:2209.06988, 2022‏ - arxiv.org
The past few decades have seen robust research on questions regarding the existence,
form, and properties of stationary distributions of stochastically modeled reaction networks …

Exponential ergodicity of continuous-time Markov chains on , with applications to stochastic reaction networks

DF Anderson, D Cappelletti, WTL Fan, J Kim - arxiv preprint arxiv …, 2023‏ - arxiv.org
This paper provides a new method that can be used to determine when an ergodic
continuous-time Markov chain on $\mathbb Z^ d $ converges exponentially fast to its …

Classification and threshold dynamics of stochastic reaction networks

C Wiuf, C Xu - arxiv preprint arxiv:2012.07954, 2020‏ - arxiv.org
Stochastic reaction networks (SRNs) provide models of many real-world networks.
Examples include networks in epidemiology, pharmacology, genetics, ecology, chemistry …

Non-explosivity of endotactic stochastic reaction systems

C Xu - arxiv preprint arxiv:2409.05340, 2024‏ - arxiv.org
Reaction networks have been widely used as generic models in diverse areas of applied
science, such as biology, chemistry, ecology, epidemiology, and computer science …

A path method for non-exponential ergodicity of Markov chains and its application for chemical reaction systems

M Kim, J Kim - arxiv preprint arxiv:2402.05343, 2024‏ - arxiv.org
In this paper, we present criteria for non-exponential ergodicity of continuous-time Markov
chains on a countable state space. These criteria can be verified by examining the ratio of …

[PDF][PDF] A new path method for exponential ergodicity of Markov processes on Z d, with applications to stochastic reaction networks

DF Anderson, D Cappelletti, WTL Fan, J Kim - 2023‏ - people.math.wisc.edu
This paper provides a new path method that can be used to determine when an ergodic
continuous-time Markov chain on Zd converges exponentially fast to its stationary …