Emerging roles for the gut microbiome in autism spectrum disorder
Autism spectrum disorder (ASD) is a serious neurodevelopmental disorder that affects one
in 45 children in the United States, with a similarly striking prevalence in countries around …
in 45 children in the United States, with a similarly striking prevalence in countries around …
The rodent forced swim test measures stress-co** strategy, not depression-like behavior
KG Commons, AB Cholanians, JA Babb… - ACS chemical …, 2017 - ACS Publications
The forced swim test (FST) measures co** strategy to an acute inescapable stress and
thus provides unique insight into the neural limb of the stress response. Stress, particularly …
thus provides unique insight into the neural limb of the stress response. Stress, particularly …
Autism spectrum disorder: focus on glutamatergic neurotransmission
Disturbances in the glutamatergic system have been increasingly documented in several
neuropsychiatric disorders, including autism spectrum disorder (ASD). Glutamate-centered …
neuropsychiatric disorders, including autism spectrum disorder (ASD). Glutamate-centered …
Genetic and non-genetic animal models for autism spectrum disorders (ASD)
Z Ergaz, L Weinstein-Fudim, A Ornoy - Reproductive Toxicology, 2016 - Elsevier
Autism spectrum disorder (ASD) is associated, in addition to complex genetic factors, with a
variety of prenatal, perinatal and postnatal etiologies. We discuss the known animal models …
variety of prenatal, perinatal and postnatal etiologies. We discuss the known animal models …
A subset of autism-associated genes regulate the structural stability of neurons
Autism spectrum disorder (ASD) comprises a range of neurological conditions that affect
individuals' ability to communicate and interact with others. People with ASD often exhibit …
individuals' ability to communicate and interact with others. People with ASD often exhibit …
Downregulation of kainate receptors regulating GABAergic transmission in amygdala after early life stress is associated with anxiety-like behavior in rodents
J Englund, J Haikonen, V Shteinikov… - Translational …, 2021 - nature.com
Early life stress (ELS) is a well-characterized risk factor for mood and anxiety disorders.
GABAergic microcircuits in the amygdala are critically implicated in anxiety; however …
GABAergic microcircuits in the amygdala are critically implicated in anxiety; however …
Kainate receptors and synaptic plasticity
Synaptic plasticity has classically been characterized to involve the NMDA and AMPA
subtypes of glutamate receptors, with NMDA receptors providing the key trigger for the …
subtypes of glutamate receptors, with NMDA receptors providing the key trigger for the …
Emerging synaptic molecules as candidates in the etiology of neurological disorders
Synapses are complex structures that allow communication between neurons in the central
nervous system. Studies conducted in vertebrate and invertebrate models have contributed …
nervous system. Studies conducted in vertebrate and invertebrate models have contributed …
Brain Specific RagA Overexpression Triggers Depressive‐Like Behaviors in Mice via Activating ADORA2A Signaling Pathway
J Zhao, Y Sun, Y Feng, J Rong - Advanced Science, 2024 - Wiley Online Library
Neuroinflammation hallmarks the pathology of depression although the etiological
complexity has not yet been resolved. Previous studies demonstrate that bacterial …
complexity has not yet been resolved. Previous studies demonstrate that bacterial …
Kainate receptors: from synaptic activity to disease
JV Negrete‐Díaz, R Falcón‐Moya… - The FEBS …, 2022 - Wiley Online Library
Kainate receptors (KARs) are glutamate receptors that participate in the postsynaptic
transmission of information and in the control of neuronal excitability, as well as …
transmission of information and in the control of neuronal excitability, as well as …