Interleukin-10 (IL-10), first recognized for its ability to inhibit activation and effector function of
T cells, monocytes, and macrophages, is a multifunctional cytokine with diverse effects on …

ABSTRACT Interleukin 10 (IL-10) is a cytokine with potent anti-inflammatory properties that
plays a central role in limiting host immune response to pathogens, thereby preventing …

The anti-inflammatory cytokines are a series of immunoregulatory molecules that control the
proinflammatory cytokine response. Cytokines act in concert with specific cytokine inhibitors …

Alzheimer′ s disease (AD) is the most common neurodegenerative disorder to date.
Neuropathological hallmarks are β‐amyloid (Aβ) plaques and neurofibrillary tangles, but the …

It is becoming increasingly apparent that probiotics are important to the health of the host.
The absence of probiotic bacteria in the gut can have adverse effects not only locally in the …

Abstract Heme oxygenase (HO)-1 catabolizes heme into three products: carbon monoxide
(CO), biliverdin (which is rapidly converted to bilirubin) and free iron (which leads to the …

We have described a murine model of IBD that was induced in CB-17 scid mice by transfer
of the CD45RBhi subpopulation of CD4+ T cells from normal BALB/c mice and could be …

The role of tumor necrosis factor (TNF) as an immune mediator has long been appreciated
but its function in the brain is still unclear. TNF receptor 1 (TNFR1) is expressed in most cell …

Lipopolysaccharide (LPS) from Gram-negative bacteria is one of the most potent innate
immune-activating stimuli known. Here we review the current understanding of LPS effects …

Cytokines orchestrate the complex netuwrk of cellular interactions that regulate effector cell
functions of natural and immune resistance. Although T cells, natural killer (NK) cells and …