Since the advent of the green fluorescent protein, the subcellular localization, mobility,
transport routes and binding interactions of proteins can be studied in living cells. Live cell …

It has long been axiomatic that a protein's structure determines its function. Intrinsically
disordered proteins (IDPs) and disordered protein regions (IDRs) defy this structure …

A particle's motion in crowded environments often exhibits anomalous diffusion, whose
nature depends on the situation at hand and is formalized within different physical models …

Diffusion of solutes and macromolecules in aqueous cellular compartments is required for
numerous cellular processes including metabolism, second messenger signaling and …

Dynamic molecular interactions are fundamental to all cellular processes. In vivo analyses of
these interactions are frequently done using fluorescence recovery after photobleaching …

Eukaryotic cells face the challenging task of transporting a variety of particles through the
complex intracellular milieu in order to deliver, distribute, and mix the many components that …

The endoplasmic reticulum (ER) is the major compartment for the processing and quality
control of newly synthesized proteins. Green fluorescent protein (GFP) was used as a …

Ca2+ is one of the most important messengers. It transmits signals inside living cells and
takes part in intercellular coordination. The dynamics of the Ca2+ concentration shows a …

Significance: In addition to their classical role in cellular ATP production, mitochondria are of
key relevance in various (patho) physiological mechanisms including second messenger …

Cell biologists have used photobleaching to investigate the lateral mobility of fluorophores
on the cell surface since the 1970s. Fusions of green fluorescent protein (GFP) to specific …