Using MetaboAnalyst 3.0 for comprehensive metabolomics data analysis

J **a, DS Wishart - Current protocols in bioinformatics, 2016 - Wiley Online Library
Abstract MetaboAnalyst (http://www. metaboanalyst. ca) is a comprehensive Web application
for metabolomic data analysis and interpretation. MetaboAnalyst handles most of the …

Analytical methods in untargeted metabolomics: state of the art in 2015

A Alonso, S Marsal, A Julià - Frontiers in bioengineering and …, 2015 - frontiersin.org
Metabolomics comprises the methods and techniques that are used to measure the small
molecule composition of biofluids and tissues, and is actually one of the most rapidly …

Using MetaboAnalyst 4.0 for comprehensive and integrative metabolomics data analysis

J Chong, DS Wishart, J **a - Current protocols in bioinformatics, 2019 - Wiley Online Library
Abstract MetaboAnalyst (https://www. metaboanalyst. ca) is an easy‐to‐use web‐based tool
suite for comprehensive metabolomic data analysis, interpretation, and integration with other …

Investigating the impact of data normalization on classification performance

D Singh, B Singh - Applied Soft Computing, 2020 - Elsevier
Data normalization is one of the pre-processing approaches where the data is either scaled
or transformed to make an equal contribution of each feature. The success of machine …

Multivariate analysis in metabolomics

B Worley, R Powers - Current metabolomics, 2013 - ingentaconnect.com
Metabolomics aims to provide a global snapshot of all small-molecule metabolites in cells
and biological fluids, free of observational biases inherent to more focused studies of …

Probabilistic Quotient Normalization as Robust Method to Account for Dilution of Complex Biological Mixtures. Application in 1H NMR Metabonomics

F Dieterle, A Ross, G Schlotterbeck, H Senn - Analytical chemistry, 2006 - ACS Publications
For the analysis of the spectra of complex biofluids, preprocessing methods play a crucial
role in rendering the subsequent data analyses more robust and accurate. Normalization is …

Nuclear magnetic resonance (NMR) spectroscopy in food science: A comprehensive review

E Hatzakis - Comprehensive reviews in food science and food …, 2019 - Wiley Online Library
Nuclear magnetic resonance (NMR) spectroscopy is a robust method, which can rapidly
analyze mixtures at the molecular level without requiring separation and/or purification …

NMR-based metabolomic analysis of plants

HK Kim, YH Choi, R Verpoorte - Nature protocols, 2010 - nature.com
Nuclear magnetic resonance (NMR)-based metabolomics has many applications in plant
science. Metabolomics can be used in functional genomics and to differentiate plants from …

Reflections on univariate and multivariate analysis of metabolomics data

E Saccenti, HCJ Hoefsloot, AK Smilde, JA Westerhuis… - Metabolomics, 2014 - Springer
Metabolomics experiments usually result in a large quantity of data. Univariate and
multivariate analysis techniques are routinely used to extract relevant information from the …

NOREVA: normalization and evaluation of MS-based metabolomics data

B Li, J Tang, Q Yang, S Li, X Cui, Y Li… - Nucleic acids …, 2017 - academic.oup.com
Diverse forms of unwanted signal variations in mass spectrometry-based metabolomics data
adversely affect the accuracies of metabolic profiling. A variety of normalization methods …