Malaria proteomics: insights into the parasite–host interactions in the pathogenic space
Proteomics is improving malaria research by providing global information on relevant
protein sets from the parasite and the host in connection with its cellular structures and …
protein sets from the parasite and the host in connection with its cellular structures and …
Landscape and dynamics of transcription initiation in the malaria parasite Plasmodium falciparum
A comprehensive map of transcription start sites (TSSs) across the highly AT-rich genome of
P. falciparum would aid progress toward deciphering the molecular mechanisms that …
P. falciparum would aid progress toward deciphering the molecular mechanisms that …
Antimalarial drug discovery: in silico structural biology and rational drug design
TAP De Beer, GA Wells, PB Burger… - … Current Drug Targets …, 2009 - ingentaconnect.com
Malaria remains one of the most burdensome human infectious diseases, with a high rate of
resistance outbreaks and a constant need for the discovery of novel antimalarials and drug …
resistance outbreaks and a constant need for the discovery of novel antimalarials and drug …
Computational Prediction of Host-Parasite Protein Interactions between P. falciparum and H. sapiens
S Wuchty - PLoS One, 2011 - journals.plos.org
To obtain candidates of interactions between proteins of the malaria parasite Plasmodium
falciparum and the human host, homologous and conserved interactions were inferred from …
falciparum and the human host, homologous and conserved interactions were inferred from …
Genome comparison of human and non-human malaria parasites reveals species subset-specific genes potentially linked to human disease
Genes underlying important phenotypic differences between Plasmodium species, the
causative agents of malaria, are frequently found in only a subset of species and cluster at …
causative agents of malaria, are frequently found in only a subset of species and cluster at …
A Chemical Proteomics Approach for the Search of Pharmacological Targets of the Antimalarial Clinical Candidate Albitiazolium in Plasmodium falciparum Using …
DM Penarete-Vargas, A Boisson, S Urbach… - PLoS …, 2014 - journals.plos.org
Plasmodium falciparum is responsible for severe malaria which is one of the most prevalent
and deadly infectious diseases in the world. The antimalarial therapeutic arsenal is …
and deadly infectious diseases in the world. The antimalarial therapeutic arsenal is …
Revisiting the Plasmodium falciparum RIFIN family: from comparative genomics to 3D-model prediction
Background Subtelomeric RIFIN genes constitute the most abundant multigene family in
Plasmodium falciparum. RIFIN products are targets for the human immune response and …
Plasmodium falciparum. RIFIN products are targets for the human immune response and …
Gene function prediction using semantic similarity clustering and enrichment analysis in the malaria parasite Plasmodium falciparum
PMR Tedder, JR Bradford, CJ Needham… - …, 2010 - academic.oup.com
Motivation: Functional genomics data provides a rich source of information that can be used
in the annotation of the thousands of genes of unknown function found in most sequenced …
in the annotation of the thousands of genes of unknown function found in most sequenced …
[HTML][HTML] Genome-wide microsatellite characteristics of five human Plasmodium species, focusing on Plasmodium malariae and P. ovale curtisi
Microsatellites can be utilized to explore genotypes, population structure, and other genomic
features of eukaryotes. Systematic characterization of microsatellites has not been a focus …
features of eukaryotes. Systematic characterization of microsatellites has not been a focus …
Identifying novel cell cycle proteins in apicomplexa parasites through co-expression decision analysis
Hypothetical proteins comprise roughly half of the predicted gene complement of
Toxoplasma gondii and Plasmodium falciparum and represent the largest class of uniquely …
Toxoplasma gondii and Plasmodium falciparum and represent the largest class of uniquely …