Malaria proteomics: insights into the parasite–host interactions in the pathogenic space

JM Bautista, P Marín-García, A Diez, IG Azcárate… - Journal of …, 2014 - Elsevier
Proteomics is improving malaria research by providing global information on relevant
protein sets from the parasite and the host in connection with its cellular structures and …

Landscape and dynamics of transcription initiation in the malaria parasite Plasmodium falciparum

SH Adjalley, CD Chabbert, B Klaus, V Pelechano… - Cell reports, 2016 - cell.com
A comprehensive map of transcription start sites (TSSs) across the highly AT-rich genome of
P. falciparum would aid progress toward deciphering the molecular mechanisms that …

Antimalarial drug discovery: in silico structural biology and rational drug design

TAP De Beer, GA Wells, PB Burger… - … Current Drug Targets …, 2009 - ingentaconnect.com
Malaria remains one of the most burdensome human infectious diseases, with a high rate of
resistance outbreaks and a constant need for the discovery of novel antimalarials and drug …

Computational Prediction of Host-Parasite Protein Interactions between P. falciparum and H. sapiens

S Wuchty - PLoS One, 2011 - journals.plos.org
To obtain candidates of interactions between proteins of the malaria parasite Plasmodium
falciparum and the human host, homologous and conserved interactions were inferred from …

Genome comparison of human and non-human malaria parasites reveals species subset-specific genes potentially linked to human disease

C Frech, N Chen - PLoS computational biology, 2011 - journals.plos.org
Genes underlying important phenotypic differences between Plasmodium species, the
causative agents of malaria, are frequently found in only a subset of species and cluster at …

A Chemical Proteomics Approach for the Search of Pharmacological Targets of the Antimalarial Clinical Candidate Albitiazolium in Plasmodium falciparum Using …

DM Penarete-Vargas, A Boisson, S Urbach… - PLoS …, 2014 - journals.plos.org
Plasmodium falciparum is responsible for severe malaria which is one of the most prevalent
and deadly infectious diseases in the world. The antimalarial therapeutic arsenal is …

Revisiting the Plasmodium falciparum RIFIN family: from comparative genomics to 3D-model prediction

E Bultrini, K Brick, S Mukherjee, Y Zhang, F Silvestrini… - BMC genomics, 2009 - Springer
Background Subtelomeric RIFIN genes constitute the most abundant multigene family in
Plasmodium falciparum. RIFIN products are targets for the human immune response and …

Gene function prediction using semantic similarity clustering and enrichment analysis in the malaria parasite Plasmodium falciparum

PMR Tedder, JR Bradford, CJ Needham… - …, 2010 - academic.oup.com
Motivation: Functional genomics data provides a rich source of information that can be used
in the annotation of the thousands of genes of unknown function found in most sequenced …

[HTML][HTML] Genome-wide microsatellite characteristics of five human Plasmodium species, focusing on Plasmodium malariae and P. ovale curtisi

VB Mathema, S Nakeesathit, NJ White, AM Dondorp… - Parasite, 2020 - ncbi.nlm.nih.gov
Microsatellites can be utilized to explore genotypes, population structure, and other genomic
features of eukaryotes. Systematic characterization of microsatellites has not been a focus …

Identifying novel cell cycle proteins in apicomplexa parasites through co-expression decision analysis

CL Butler, O Lucas, S Wuchty, B Xue, VN Uversky… - PLoS …, 2014 - journals.plos.org
Hypothetical proteins comprise roughly half of the predicted gene complement of
Toxoplasma gondii and Plasmodium falciparum and represent the largest class of uniquely …