Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by
persistent articular inflammation and joint damage. RA was first described over 200 years …

The term inflammatory arthritis defines a family of diseases, including rheumatoid arthritis
(RA), caused by an overactive immune system, and influenced by host aspects including …

Rationale: Angiogenesis expedites tissue impairment in many diseases, including age-
related macular degeneration (AMD), a leading cause of irreversible blindness in elderly. A …

Ischemic stroke is a significant global health issue, ranking fifth among all causes of death
and a leading cause of serious long‐term disability. Ischemic stroke leads to severe …

Vasoinhibin, a proteolytic fragment of the hormone prolactin, inhibits blood vessel growth
(angiogenesis) and permeability, stimulates the apoptosis and inflammation of endothelial …

The hormone prolactin acquires antiangiogenic and antivasopermeability properties after
undergoing proteolytic cleavage to vasoinhibin, an endogenous prolactin fragment of 123 or …

Inflammatory arthritis defines a family of diseases influenced by reproductive hormones.
Vasoinhibin, a fragment of the hormone prolactin (PRL), has antiangiogenic and …

Neovascularization in rheumatoid arthritis (RA) is a key bridge between malignant
proliferative synovial tissue and pannus. In view of previous studies on the efficacy of …

Abstract Prolactin (PRL) is a 23-kDa protein synthesized and secreted by lactotroph cells of
the anterior pituitary gland but also by other peripheral tissues. PRL binds directly to a …

Introduction Circulating levels of the antiangiogenic protein vasoinhibin, a fragment of
prolactin, are of interest in vasoproliferative retinopathies, preeclampsia, and peripartum …