Opioids are used increasingly for chronic non-cancer pain. Controversy exists about their
effectiveness and safety with long-term use. We analysed available randomised, placebo …

The classical view of emotion hypothesizes that certain emotion categories have a specific
autonomic nervous system (ANS)“fingerprint” that is distinct from other categories …

The numbers of cases and deaths from coronavirus disease 2019 (COVID-19) are
continuously increasing. Many people are concerned about the efficacy and safety of the …

Basic life science literature is rich with information, however methodically quantitative
attempts to organize this information are rare. Unlike clinical research, where consolidation …

Study Objectives: We performed a systematic review of the OSA-related risk of crash in
commercial motor vehicle (CMV) drivers. The primary objective involved determining …

Background Inadequate pain management after surgery increases the risk of postoperative
complications and may predispose for chronic postsurgical pain. Perioperative ketamine …

This paper sets out a generalised linear model (GLM) framework for the synthesis of data
from randomised controlled trials (RCTs). We describe a common model taking the form of a …

Objective: To quantify the antiemetic efficacy and adverse effects of cannabis used for
sickness induced by chemotherapy. Design: Systematic review. Data sources: Systematic …

Background In the past decade, multiple studies have examined the effectiveness of
Acceptance and Commitment Therapy (ACT) for substance use disorders relative to other …

Signals (or cues) are added to multimedia learning materials to guide learners' attention to
critical elements of the materials. Yet, research on signaling has produced mixed findings on …