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Obesity, adipose tissue and vascular dysfunction
Cardiovascular diseases are the leading cause of death worldwide. Overweight and obesity
are strongly associated with comorbidities such as hypertension and insulin resistance …
are strongly associated with comorbidities such as hypertension and insulin resistance …
Mechanistic links between obesity, diabetes, and blood pressure: role of perivascular adipose tissue
Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …
Adipose tissue distribution and morphology play a key role in determining the degree of …
Epicardial and perivascular adipose tissues and their influence on cardiovascular disease: basic mechanisms and clinical associations
It is well established that the cardiovascular (CV) risk of obesity is more strongly associated
with visceral rather than subcutaneous adiposity. 1–3 Anthropometric variables that account …
with visceral rather than subcutaneous adiposity. 1–3 Anthropometric variables that account …
The role of perivascular adipose tissue in obesity‐induced vascular dysfunction
Under physiological conditions, perivascular adipose tissue (PVAT) attenuates agonist‐
induced vasoconstriction by releasing vasoactive molecules including hydrogen peroxide …
induced vasoconstriction by releasing vasoactive molecules including hydrogen peroxide …
Retinal vascular caliber, cardiovascular risk factors, and inflammation: the multi-ethnic study of atherosclerosis (MESA)
purpose. To describe the relationship of retinal arteriolar and venular caliber with
cardiovascular risk factors, including inflammatory biomarkers, in a multiethnic population of …
cardiovascular risk factors, including inflammatory biomarkers, in a multiethnic population of …
Increased urinary albumin excretion, endothelial dysfunction, and chronic low-grade inflammation in type 2 diabetes: progressive, interrelated, and independently …
In 328 type 2 diabetic patients followed for 9.0 years (mean), we investigated whether
endothelial dysfunction and chronic inflammation (estimated from plasma markers) can …
endothelial dysfunction and chronic inflammation (estimated from plasma markers) can …
Endothelial dysfunction in obesity and insulin resistance: a road to diabetes and heart disease
AE Caballero - Obesity research, 2003 - Wiley Online Library
Obesity, insulin resistance, and endothelial dysfunction closely coexist throughout the
natural history of type 2 diabetes. They all can be identified not only in people with type 2 …
natural history of type 2 diabetes. They all can be identified not only in people with type 2 …
Leptin and atherosclerosis
J Beltowski - Atherosclerosis, 2006 - Elsevier
Leptin, a 167-amino acid peptide hormone produced by white adipose tissue, is primarily
involved in the regulation of food intake and energy expenditure. Leptin receptors are …
involved in the regulation of food intake and energy expenditure. Leptin receptors are …
[PDF][PDF] Adipocytokines novel link between inflammation
TJ Guzik, D Mangalat, R Korbut - J. Physiol. Pharmacol, 2006 - researchgate.net
Ceretain treatments may lead to significant changes in adipocytokine levels. For example
include beta-2 adrenoreceptor agonists, thiazolidinediones as well as androgens lead to …
include beta-2 adrenoreceptor agonists, thiazolidinediones as well as androgens lead to …
Leptin signaling and obesity: cardiovascular consequences
Leptin, among the best known hormone markers for obesity, exerts pleiotropic actions on
multiple organ systems. In this review, we summarize major leptin signaling pathways …
multiple organ systems. In this review, we summarize major leptin signaling pathways …