The aryl hydrocarbon receptor (AhR) is an evolutionarily old transcription factor belonging to
the Per-ARNT-Sim–basic helix-loop-helix protein family. AhR translocates into the nucleus …

The indolocarbazoles are an important class of nitrogen heterocycles which has evolved
significantly in recent years, with numerous studies focusing on their diverse biological …

Age is the dominant risk factor for most chronic human diseases, but the mechanisms
through which ageing confers this risk are largely unknown. The age-related acquisition of …

Rapid cut‐off of blood supply in diseases involving thrombosis is a major cause of morbidity
and mortality worldwide. However, the current thrombolysis strategies offer limited results …

Induced pluripotent stem cells (iPSCs), and cells derived from them, have become key tools
for modeling biological processes, particularly in cell types that are difficult to obtain from …

For decades, the aryl hydrocarbon receptor (AHR) was studied for its role in environmental
chemical toxicity ie, as a quirk of nature and a mediator of unintended consequences of …

The endogenous ligand-activated aryl hydrocarbon receptor (AHR) plays an important role
in numerous biologic processes. As the known number of AHR-mediated processes grows …

Vascular and haematopoietic cells organize into specialized tissues during early
embryogenesis to supply essential nutrients to all organs and thus play critical roles in …

Tumour microenvironment is a complex ecosystem in which myeloid cells are the most
abundant immune elements. This cell compartment is composed by different cell types …

The aryl hydrocarbon receptor (AHR) was for many years of interest only to pharmacologists
and toxicologists. However, this protein has fundamental roles in biology that are being …